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Simplicef
Frequently Asked Questions
Simplicef is a prescription medication antibiotic used for a wide range of infections, most commonly of the skin, urinary tract, bones, and respiratory tract.
Simplicef is for dogs.
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Treats many different types of infections such as respiratory tract, as well as ear, skin, and urinary tract infections
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Kills many types of bacteria
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Convenient, once-a-day dosing
Simplicef kills bacteria by interfering with the bacteria's ability to build a cell wall. It is effective against most gram-positive and gram-negative bacteria.
No, not in a once-a day dosing form.
Simplicef tablets are given orally and can be given with food.
Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian. Use all of the medication prescribed, even if your pet appears well. If the entire course of treatment is not given, the infection may recur or worsen.
This medication should only be given to the pet for whom it was prescribed.
Simplicef is well absorbed from the intestinal tract and is carried by the blood stream to many tissues of the body. To be effective, Simplicef must be given for multiple days in a row. If doses are missed or the entire treatment regimen is not completed, the infection could recur or worsen. Consult your veterinarian if the animal's condition does not improve or worsens after beginning treatment with Simplicef.
Simplicef comes in tablet form.
Cefpodoxime proxetil (a cephalosporin)
Talk to your veterinarian about what tests and exams may be necessary while your pet is taking Simplicef. Also discuss how long the treatment period will be and what type of outcome is expected.
Tell your veterinarian if your pet may be pregnant or is nursing, or if you intend to breed your pet.
Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
Follow your veterinarian's directions and give the full course of Simplicef as prescribed. Consult your veterinarian if your pet's condition does not improve or worsens after beginning treatment with Simplicef.
Do not use in animals hypersensitive (allergic) to them. Do not use in animals hypersensitive to penicillins, as they may react to both. Although no fetal abnormalities from cephalosporin use have been documented, do not use in pregnant or lactating animals (female animals nursing their young) if possible, as cephalosporins cross to the fetuses and pass in the milk. Use with caution in animals with seizures, epilepsy, or kidney disease.
Side effects are rare. You may see lack of appetite, vomiting, or diarrhea. If you observe any of the above signs in your pet, contact your veterinarian.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
Store at room temperature in a tight, light-resistant, childproof container. Keep out of reach of children and pets.
May see vomiting or diarrhea. With high doses or long-term use, may see liver disease, which may cause jaundice (yellowing of the gums, skin, or eyes); kidney damage, usually with increased drinking and urination; blood disorders, which may cause decreased white blood cells and platelets, causing an increased tendency to bruise or bleed; and damage to the nervous system.
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
Consult your veterinarian before using cephalosporins with vitamins, supplements, aminoglycosides (gentamicin, neomycin) or amphotericin B, anticoagulants (blood thinners, such as heparin or warfarin), and probenicid, since interactions may occur.
Some cephalosporins may affect some tests for urine glucose. May cause a false-positive test result with some brands of urine test strips dipsticks used to check urine glucose.
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What’s the difference in cephalexin and simplicef
I accidently gave my 70 lb dog a second dose of 150 mg of simplicef. Do I need to be worried?
I accidentally gave Lina her antibiotic 2x a day for 2 days. The pepsid was supposed to be 2x a day and the simplicef 1x a day (300 mg)
Tot is being treated with Simplicef for a respiratory infection. She also has heart disease and takes vetmedin, enalapril, and Salix. She has no appetite (she acts like she wants to eat it, but just pushes it around and seems confused by it) and after 6 days, I don't see any change in the respiratory symptoms. She has had this before, and I don't remember it taking this long for her to get better. Is this abnormal? She has 6 more days on the simplicef.
Hi, our 19 lb dog was prescribed Simplicef (.5 100mg pill every 24 hours ). Unfortunately, I accidentally gave her the whole pill tonight instead of half a pill (double dose). Is this ok, do we need to find an emergency vet? Should we just watch her overnight for signs of distress (e.g., diarrhea, vomiting)?
Hello, my dog gets a rash all over his body that looks like chicken pox he gets it 3-4 times per year since he was a puppy I have take him to a lot of vets and they only give us simplicef which helps a lot and the bumps go away. But every visit and refill is expensive and we will like to know if there’s something that can completely stop it.
My 2 1/2 yr old dog feels very hot. I took his temperature and it is 101.2 degrees. He was diagnosed w/ a skin infection a couple of weeks ago and prescribed Simplicef. The original raw, red area cleared up but now he has these sore like things on his paws. He also has bald spots on his head and behind his ears. We have an appt Tue w/ his vet. Okay to wait to see her?
My dog has been battling an ongoing paw issue. His paws get red and inflamed between the pads, and eventually boils and pustules form. Then a bacterial infection sets in. I have had him on and off antibiotics for 6 months (Simplicef). 3 week runs of antibiotics at a time. His paws are sentistive to touch and always very red and sore. I’ve tried changing his food and nothing helps. He has also lost the hair on his tail. The vet said it’s Pododermatitis and that there is no real cure. Please help!
Bella was put on Cephalexin 500 mg 3 times a day until gone. She was also put on Temaril-P tablets 1 1/2 tablets twice a day until gone. She was also given a spray for the hot spot which is Betagen Topical spray 120mL twice a day until healed.
Rumple was on Cephalexin 750mg twice a day for a total of 17 days (with a three day break after 7 days) he finished them November 1st 2018. For the last 7 days he was also on Fortiflora Canine PVD. Since being on the antibiotics his poos have continued to be abnormal, although, some times they seem to be getting closer to normal colour and consistency but then they go back to being partly clay-like texture on one end and degreasing to more difficult to pick up near the finish. Bio has more info.
Is giving my small barely under 19 lb. 13 and a half years old little Sheltie dog half of a 100 mg Tablet of Cefpodoxime once every 24 hours on schedule with food, treatment alone for 8 days, correct, wise, sufficient Veterinary Care for my little 13 and a half year old male Shetland Sheepdog's likely Kidney Infection?
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