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Methimazole treats hyperthyroidism in cats, a condition in which too much thyroid hormone is produced. It will not cure the disease, but will usually control it if given for the rest of the cat's life.
Methimazole may also be used to protect the kidneys in dogs receiving cisplatin, an anti-cancer drug.
Dogs and Cats.
Controls the symptoms of hyperthyroidism for an improved quality of life
Treats hyperthyroidism without surgery or anesthesia
Affordable per-tablet price!
Methimazole reduces the amount of thyroid hormone produced by the thyroid gland.
Methimazole tablets are given by mouth. The tablet form is very bitter, and it may be difficult to administer. Use a "pill pocket" treat or hide it in your pet's favorite treat. Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.
Blood levels of thyroid hormone will be checked by your veterinarian at regular intervals, and the dose increased or decreased as needed. The lowest effective dose should be used.
This medication should only be given to the pet for whom it was prescribed.
In most cases methimazole will lower the level of thyroid hormone in hyperthyroid cats. It will generally take 1-3 weeks before the level of thyroid hormone produced by the body will start to decrease. Methimazole will not cure the disease, but will usually control it if given for the rest of the cat's life.
Tablet form.
Please click on "More Information" for possible drug and food interactions with this medication.
Tapazol
meth-EYE-miz-zal
Methimazole
Talk to your veterinarian about what tests and exams may be necessary while your pet is taking Methimazole. Also, discuss what type of outcome is expected. Have your veterinarian explain the other treatment options for hyperthyroidism in cats.
Tell your veterinarian if your pet has a blood disease, liver disease, or autoimmune disease; or may be pregnant, is nursing, or if you intend to breed your pet.
Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
Methimazole will not cure the disease, but will usually control it if given for the rest of the cat's life. Follow your veterinarian's dosage instructions carefully. Side effects are most common during the first 3 months of treatment. Methimazole has a very bitter taste.
Not for use in pets who are hypersensitive (allergic) to it. Use with extreme caution in pets with anemia, clotting disorders, bleeding, low white cell and platelet counts, or diseases of the immune system, liver, or kidney.
Use with extreme caution in pregnant or lactating animals (females nursing their young). If the mother is receiving Methimazole, place the young on milk replacer after they have received the colostrum (first milk immediately after birth).
In addition to monitoring of thyroid hormone levels, laboratory tests to check liver and kidney function and blood cell counts may be performed before starting treatment and then regularly thereafter.
Side effects tend to occur in the first three months of treatment. If you observe any of the effects listed below, contact your veterinarian immediately.
May see loss of appetite, vomiting, or lethargy. These usually occur within the first two weeks of treatment and may stop even with continuation of treatment.
Less common side effects include liver problems resulting in the above signs plus yellowing of the gums, skin, or eyes; itching of the face, resulting in scratching; or bleeding tendencies. Your veterinarian will determine if these effects necessitate stopping the medication and treating with surgery or radioactive iodine therapy.
Treatment with Methimazole may unmask hidden kidney disease.
Rarely, you may see the development of myasthenia gravis, a neuromuscular disease that severely weakens muscles and may cause difficulty swallowing. If your pet is unusually tired, has a fever (temperature over 103°F), or shows signs of bruising or bleeding, contact your veterinarian immediately.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, and sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
Store tablets at room temperature in a tightly closed container protected from light. Refrigerate oral suspension. Keep away from children and pets.
If you know or suspect your pet has had an overdose, contact your veterinarian immediately. Signs of an overdose are similar to the common side effects listed above.
Consult your veterinarian before using Methimazole with any other medications, including vitamins and supplements, since interactions may occur. The drugs clomipramine, amitriptylline, omeprazole, and cyclophosamide may interact with Methimazole and cause severe side effects.
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My 17 yr old cat has been diagnosed with hyperthyroidism. she was started on Methimazole chew treats and now refuses to eat them. I switched to the twist a dose ear Methimazole but if I give that to her daily like the vet suggested, all she does is sleep day and night. It seems to knock her out right after I apply it to her ear. then she starts vomiting her food. I am beginning to think we would be better off going with the radioactive iodine thing. what do you think?
HI, My 13yr old female cat is on Transdermal Methimazole, 5mg, 2x day, by syringe. However, my cat won't let me near her to apply this to her ear!!! I now have broken the trust
Can tony take a lysine supplement with his other meds:amlodipine besylate, methimazole, tumil K potassium supplement and mirtazapine appetite stimulant? He also eats a kidney diet and I wonder if the powder lysine supplement may flavor the food and make him like it better? Thanks!!
Hello, does my 13 y/o cat's bloodwork indicate kidney problems? Please see attachment. He is on methimazole and prednisolone for hyperthyroid and bronchitis. Also, would he benefit from canned sardines in water without add salt? Thank you!
Hello! Regarding homemade diet for my 15 y/o hyperthyroid and early CKD cat-- 1) Due to hyperthyroidism, is it ok to leave out iodine salt in the recipe? The methimazole keeps the TT4 at around 1.7. 2) Is it true that dark meat has lower phosphorous levels and is a better protein choice than say ground beef? Thank you!
Hi! Tony is on methimazole and his most recent labwork Says his thyroid level is 1.8. Is this is a normal level? I ask because he lays by his water bowl a lot but his kidney levels are good but I was told hyperthyroidism can cause extreme thirst...1.8 is not considered hyperthyroidism right? He also takes amlodipine for High blood pressure. Thx!
Hello, Beau has a urine specify gravity of 1.018 in the morning. In addition to the recent bloodwork (attached), what can be said about his health? He is on prednisolone and methimazole. Should I do USG through different time of the day? How can I use USG to better assess his health? Thank you.
My 12 year old cat has hyperthyroidism. He was diagnosed 6 months ago. We treated him with Methimazole for a month and he improved. Shortly after his refill (one month) he started to vomit after every dose. We've tried the y/d food and his levels were still high. I have to decide about radioactive iodine, and I would love an expert opinion. I have more detail, just can't fit it here.
Hi Tony’s methimazole dosage was just increased a few days ago (on Wednesday) because his thyroid levels in his lab work showed an increase from 3 months ago. How long will the increase in dosage take to regulate his thyroid because his appetite is a little off and I wonder if it’s due to this. He also takes 1/8 mrtazapine every day but it doesn’t seem to help the appetite much. Thank you
My 18-year-old cat has had borderline hyperthyroidism for several years but has been on meds for only the last 1-2 years: 30mg gabapentin 2x daily [arthritis]; 5mg prednisolone daily; and methimazole [1/2 of 5mg tablet in AM, 1/4 of 5mg tab in PM]. For the last 2-3 days, she has been peeing while lying down and/or sleeping. And the water she is drinking seems to be running through [peeing twice in one hour]. How likely could it be that she is going into renal failure?
Hi, I hope to get a 2nd opinion on Beau's lab results. Vet wants to start subq fluid and Azodyl. How severe is his CKD? How is his liver? His T4 is 1.0 and vet wants to lower methimazole from 10mg per day to 7.5 mg per day. Is it better to split 7.5 mg evenly, or can I give 5mg in AM and 2.5mg PM? Also the vet wants to stop predinisolone (for bronchitis) completely. Is that for the sake of CKD and liver and heart murmur? Thank you!
Hello my vet has decided to put tony on a potassium supplement tablet because his labs show a potassium level of 3.1 but all his kidney values are normal. He is already on amlodipine and methimazole for hi blood pressure and hyperthyroidism. My question is, when we check potassium again in 2 weeks, if the potassium supplement raises his potassium level to a normal range , does he remain on the supplement indefinitely? .. or will it take more than 2 weeks to normalize his potassium level? Thx