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Related Articles & Questions
- Health & Wellbeing
Interceptor vs. Heartgard: Guide to Heartworm & Worm Prevention
Search Petco to find the benefits of both Interceptor and Heartgard worm medicines for dogs. We strive to help you keep your pup happy and healthy.
Updated on October 29th, 2025
- Health & Wellbeing
Interceptor vs. Interceptor Plus: Best Heartworm & Worm Med for Dogs
At Petco, learn more about the benefits & differences of Interceptor & Interceptor Plus dewormer for dogs with heartworm, roundworms, hookworms & tapeworms.
Updated on October 29th, 2025
Health & WellbeingGalliprant for Dogs: Relieve Arthritis Pain, Dosing & Side Effects
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- Health & Wellbeing
Enalapril for Pets: Treat Heart, Kidney & Blood Pressure Effectively
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- Health & Wellbeing
Simparica Trio vs. Trifexis: Best Flea & Tick Med for Your Dog?
Unsure which flea & tick medication to choose for your pup? Check out our comparison of Simparica Trio vs. Trifexis to see which product will work best for your dog!
Updated on October 29th, 2025
- Health & Wellbeing
What exactly is Centrine supposed to do? My dog has been ill because he got into something he shouldn't have, but there's no obstruction. He keeps some food down, keeps water down, has appetite, is still playful. Dr. heard lots of gurgling in the s
Regarding Centrine specifically, it is supposed to reduce GI spasms and decrease stomach acid production. Here is a good summary on the drug: https://www.petcoach.co/article/aminopentamide-centrine/
Updated on August 12th, 2025
- Health & Wellbeing
Simba used to get Heartguard and Frontline every month, but we have moved to Panama, where Heartguard is no longer available. What medicines are equivalent to Heartguard, please?
Fortunately, there are a number of heartworm preventatives similar to Heartgard, including TriHeart Plus and Iverhart. Other options for heartworm prevention have different active ingredients and include Trifexis, Interceptor, Sentinel, Revolution, and Advantage Multi. Simba's vet will be able to prescribe another option and make sure that Simba has had a recent heartworm test.
Updated on August 12th, 2025
- Health & Wellbeing
My veterinarian is prescribing vethical comboguard, I've heard some bad things, is it safe enough or should I try something else?
This drug appears to be a generic form of the drug Trifexis, which is used to prevent heartworms, intestinal parasites and fleas. Most dogs take this drug without issue. The most common side effect is vomiting or GI upset and giving the drug with a meal can help decrease the chances of this. I have had a few pets seem lethargic the day they take the medication, but that is the most severe side effect I have noted. It is not recommended in dogs with a history of seizures. You can find all sorts of scary reports on the internet about different drugs and food people are convinced killed their dogs, but often these people are just looking for an easy explanation for what happened to their dog and most of the time the heartworm prevenatative is NOT the cause of what happened. You can review their safety information and product label at http://vethical.com/dogs/comboguard/. If you still feel uncomfortable using the product you can ask your vet for a different medication for heartworms a
Updated on August 12th, 2025
- Health & Wellbeing
Is there a certain brand of flea and tick and heart worm medication that is best for my dog? Or are injectables more preferable? He’s currently on Nexgard and Heartgard. I just want to hear opinions and see other options.
Nexgard is an excellent choice for fleas and ticks, and is one of the products I recommend most frequently. I generally prefer Sentinel for heartworm prevention rather than Heartgard, as it covers a wider range of intestinal parasites and also seems to be more effective at preventing heartworm infection, especially in areas with lots of heartworm disease such as the southern/southeastern US.
Updated on August 12th, 2025
- Health & Wellbeing
Is their any difference between "Heartgard Plus" and "Tri-Heart Plus"? What purposes does CBD oil have for Canines?
Your dog is so handsome! Both Heartgard Plus and Tri-Heart Plus protect against heart worms, but I personally like Heartgard Plus best. As of yet, we have very little research on CBD oil in veterinary patients, so we cannot make any recommendations one way or the other about this product - we do not know what an appropriate dose might be, and if there are any potential health concerns or drug interactions in dogs. In addition, because it's a schedule 1 drug, it's illegal for us to prescribe or recommend. I hope this helps!
Updated on August 12th, 2025
