My dog with epilepsy got a double Keppra dose. What should I do?

Luckily Keppra has a large safety index, meaning that 20x the therapeutic level (1,200mg/kg) can be given and only cause mild symptoms (salivation and vomiting). Your pet should be ok after receiving 1500 mg at once b/c this is a dosage of 36mg/kg). No need to induce vomiting or visit your ER vet. You can return to his normal 2 pills at his next schedule dosage. I would also recommend just informing your vet for proper record keeping. Thanks for visiting Petco Pet Education Center, formerly Petcoach! Take care.

Hello, Keppra has a wide safety margin and very high dosages have been reported to cause increase salivation. The zonisamide is 2 times the high end of normal, but not near the dose where it could be dangerous. You may note that Molly is sedate, lethargic, she may have some vomiting or wobbly walk. You should contact your veterinarian in the morning to see if they want you to continue normal dosing times or if you should change the timing. Monitor for any overly sedate behavior or obtundation and contact your emergency veterinarian if you note any. Best of luck and hope this helps.

Hello. We do use Keppra in dogs, & this would have been a bit on the lower dosing side, so I would not be concerned. A potential dangerous dose would need to be at least 10 times this much. You might notics a little decreased alertness for a couple of hours, but not much else. Thanks for using Petco Pet Education Center, formerly Petcoach.

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! It is fine to give him the 1/2 tablet even if he could have gotten it. Getting an extra half won’t hurt him. I wouldn’t want him to seizure either. Have a good night!

Hello and thank you for contacting Petco Pet Education Center, formerly Petcoach. Opie will be fine. He may show signs of sedation, lethargy and sleepiness for 8-12hrs but there should not be any more worrying signs. Please, continue with the next dose of phenobarbital as normal.

Pearl will likely be fine with one extra dose, but I would call your vet first thing tomorrow morning to see if she should get her regular dose then. To be on the safe side, keep an eye out for any lethargy, vomiting, or diarrhea. I hope that helps!

The average dose for an 8 pound dog is about 1/2 of a 2.5 mg tablet. A full tablet is higher than double the dose but still within a fairly safe range. There should not be any major concern with the 2 medications together, however all patients react differently and all seizure patients are unique in what can trigger an event in them. If you have any concerns about how she is feeling or acting then I would highly encourage you to have her evaluated by your veterinarian as soon as possible. Best of luck and thank you for using Pet Coach.