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Pet Pharmacy/
Prescription Flea & Tick Medicine

Prescription Flea & Tick Medicine

Fun ON. Bugs OFF. $10 OFF $50+ flea & tick prevention orders with in-store pickup.

RX Flea & Tick for Dogs
RX Flea & Tick for Cats

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NexGard (afoxolaner) Flea and Tick Soft Beef Flavored Oral Chewables for Dogs 24.1 - 60 lbs. (Purple)
(739) reviews
+ More Choices Available
Simparica Trio for Dogs 5.6-11 lbs.
(139) reviews
+ More Choices Available
NexGard (afoxolaner) Flea and Tick Soft Beef Flavored Oral Chewables for Dogs 10.1 - 24 lbs. (Blue)
(708) reviews
+ More Choices Available
Simparica Trio for Dogs 44.1-88 lbs.
(365) reviews

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Simparica Trio for Dogs 11.1-22 lbs.
(283) reviews
+ More Choices Available
Heartgard Plus Chewable Tablets for Dogs 1 - 25 lbs. (Blue)
(1201) reviews
Bravecto Chews for Dogs 44-88 lbs
(416) reviews
$84.99
+ More Choices Available
Simparica Trio for Dogs 22.1-44 lbs.
(233) reviews

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NexGard (afoxolaner) Flea and Tick Soft Beef Flavored Oral Chewables for Dogs 60.1 - 121 lbs. (Red)
(653) reviews
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Heartgard Plus Chewable Tablets for Dogs 51 - 100 lbs. (Brown)
(1084) reviews
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Heartgard Plus Chewable Tablets for Dogs 26 - 50 lbs. (Green)
(581) reviews
Bravecto Chews for Dogs 9.9-22 lbs
(333) reviews
$80.99
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Simparica Trio for Dogs 88.1-132 lbs.
(77) reviews
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NexGard (afoxolaner) Flea and Tick Soft Beef Flavored Oral Chewables for Dogs 4 - 10 lbs. (Orange)
(238) reviews
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Revolution Plus Topical Solution 5.6-11 lbs. Cat
(120) reviews
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Interceptor Plus Chewables for Dogs 50 to 100 lbs.
(243) reviews
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Simparica Chewable for Dogs 11.1-22 lbs.
(53) reviews
Sentinel Flavor Tabs for Dogs 11 to 25 lbs
(164) reviews
$53.99
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Credelio Chewable Tablets for Dogs 12.1-25 lbs
(30) reviews
Bravecto Chews for Dogs 4.4-9.9 lbs
(98) reviews
$79.99
Bravecto Chews for Dogs 22-44 lbs
(249) reviews
$83.99
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Credelio Chewable Tablet for Dogs 50.1-100 lbs
(28) reviews
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Interceptor Plus Chewables for Dogs 25 to 50 lbs
(152) reviews
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Interceptor Plus Chewables for Dogs 8 to 25 lbs.
(186) reviews
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Revolution Topical Solution for Cats 5.1-15 lbs
(256) reviews
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Simparica Chewable for Dogs 22.1-44 lbs.
(39) reviews
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Trifexis Chewable Tablets for Dogs 10.1 to 20 lbs
(150) reviews
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Trifexis Chewable Tablets for Dogs 20.1 to 40 lbs
(98) reviews
Bravecto Chews for Dogs 88-123 lbs
(68) reviews
$84.99
Tri-Heart Plus Chewable Tablets for Dogs 1 to 25 lbs.
(162) reviews
$29.99
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Revolution Plus Topical Solution 11.1-22 lbs. Cat
(149) reviews
Tri-Heart Plus Chewable Tablets for Dogs 51 to 100 lbs.
(206) reviews
$52.99
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Advantage Multi Topical Solution for Cats 9.1 to 18 lbs
(62) reviews
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Trifexis Chewable Tablets for Dogs 60.1 to 120 lbs
(116) reviews
Bravecto 1-Month Chews for Dogs 44-88lbs
(12) reviews
$28.99
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Revolution Topical Solution for Dogs 40.1- 85 lbs
(84) reviews
Sentinel Spectrum Chewables for Dogs 50.1 to 100 lbs.
(50) reviews
$81.99
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Advantage Multi Topical Solution for Dogs 9.1 to 20 lbs
(50) reviews
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Revolution Topical Solution for Dogs 5.1-10 lbs
(59) reviews
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Credelio Chewable Tablet for Dogs 6.1-12 lbs
(19) reviews

Sentinel Flavor Tabs for Dogs 26 to 50 lbs
(113) reviews
$63.99
Iverhart Plus Chewable Tablets for Dogs 26 to 50 lbs.
(8) reviews
$37.86
Bravecto Plus Topical Solution for Cats Greater Than 6.2-13.8 lbs
(26) reviews
$55.99
Bravecto 1-Month Chews for Dogs 22-44lbs
(4) reviews
$28.99
SENERGY TOPICAL 5.1-15 lbs. for Cats
(9) reviews
$47.90
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Trifexis Chewable Tablets for Dogs 40.1 to 60 lbs
(92) reviews
Bravecto Topical Solution for Cats 6.2-13.8 lbs
(62) reviews
$76.99
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Simparica Chewable for Dogs 44.1-88 lbs.
(74) reviews

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Related Articles & Questions

New Pet
Protect Your Pet: Flea & Tick Control Solutions for Dogs & Cats
Learn how to remove flea and ticks. Petco has flea and tick removal services for dogs and cats. Get fleas and ticks removed at your neighborhood Petco.
Updated on July 28th, 2026
Health & Wellness
How Long After Pest Control Is It Safe for Pets?
You may have heard that flea and tick prevention are crucial for dogs and cats, but do you know why? Petco is sharing why and how to prioritize pest prevention for your pet.
Updated on June 19th, 2026
Health & Wellness
Flea & Tick Prevention: Oral vs. Topical - What's Best for Your Pet?
Most pet parents are familiar with topical or oral flea and tick preventives. So which is better for your pet—topical or oral?
Updated on October 23rd, 2025
Health & Wellness
Flea Infestation in Dogs & Cats: Symptoms, Treatment & Prevention
Read more about the different types of flea treatments and how they work to help eliminate fleas from your pet for their safety and happiness.
Updated on June 19th, 2026
Health & Wellness
Can You Switch Flea and Tick Medicine?
At some point in your pet’s life, you might want to switch from one flea and tick medication to another. So, how do you make the transition?
Updated on June 19th, 2026
Health & Wellness
Can Petco vets prescribe flea and tick medicine for my dog or cat?
Petco carries a variety of flea and tick medication over the counter. You can only get a prescription product from a veterinarian if they have examined Bruno. Petco does offer vaccine clinics but you would need to check with the specific services individually. Here is a link: https://www.vetcoclinics.com/ I hope this helps and please feel free to post any additional questions.
Updated on September 24th, 2025
Health & Wellness
What are the best prescription flea and tick chews for my dogs?
The easiest way to do so is to go to your veterinarian and either buy the chews from him or get a prescription from your vet and get them over the internet. I am assuming you are looking to buy either Bravecto, Simparica or Nexgard. These are prescription only.
Updated on September 24th, 2025
Vet Q & A
Where can I get affordable Nexgard for my dog's prescription?
You can find this product at any of the online veterinary pharmacies. In order to find the best value I would recommend going on goodrx.com. On this website you will be able to type in the medication and dose and it will provide you with coupon codes and the location of where you need to obtain the product. Regardless of what site you use you will still need to obtain a prescription from your veterinarian. I always caution my clients when they are planning to purchase these types of products from pharmacies of unknown origin as we cannot be certain how the drugs are being stored and what source they are obtaining the drugs from. Do your due diligence before deciding on which place to use. I have had relatively good experiences with Valley Vet Supply.
Updated on September 24th, 2025
Vet Q & A
How to get prescription flea chews for my dog without a vet?
Unfortunately we cannot provide any prescription through this website as legally we would need to physically assess your Oliver to be able to prescribe any medication. Unfortunately the only way to have an OTC flea treatment is to buy one at the local pet shop if a local vet is not available.
Updated on September 24th, 2025
Vet Q & A
Should I buy flea, tick, heartworm medicine online or from my vet?
Hi and thanks for using Petco Pet Education Center, formerly Petcoach! Good question! In general it is best to purchase these medications from your veterinarian. When purchased through a veterinarian the company will most often guarantee the effectiveness. This is usually not the case with products bought online or over the counter. When sold through a veterinarian the company that manufactures the product will stand behind the product and often pay for medical treatment should the product not work for some reason. The veterinarian also knows how to properly store the product so that it does not get damaged or becomes ineffective. Finally, sometimes over the counter products or products sold online can be counterfeit or even dangerous to use. Your veterinarian also knows what particular products tend to be most effective for your location.
Updated on September 24th, 2025

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