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My dog accidentally took double Keppra and Zonisamide. Is it serious?
Updated on September 23rd, 2025
Pet's info: Dog | Mixed Breed Large (61lb +) | Female | spayed | 9 years and 7 months old | 88 lbs
My dog takes 750mg Keppra and 400mg zonisamide twice a day. Tonight she got her pills twice by accident 90 minutes apart. She seems fine but is this serious?
1 Answer
Most Helpful Answer
Answered By Rodrigo Roca, DVM
Veterinarian
Published on September 28th, 2017
Hello, Keppra has a wide safety margin and very high dosages have been reported to cause increase salivation. The zonisamide is 2 times the high end of normal, but not near the dose where it could be dangerous. You may note that Molly is sedate, lethargic, she may have some vomiting or wobbly walk.
You should contact your veterinarian in the morning to see if they want you to continue normal dosing times or if you should change the timing.
Monitor for any overly sedate behavior or obtundation and contact your emergency veterinarian if you note any.
Best of luck and hope this helps.
You should contact your veterinarian in the morning to see if they want you to continue normal dosing times or if you should change the timing.
Monitor for any overly sedate behavior or obtundation and contact your emergency veterinarian if you note any.
Best of luck and hope this helps.
1Pet Parents found this answer helpful