Why are my newborn kittens weak and can't use their front legs?

If your cat is suddenly very weak, disoriented and unable to walk normally it is best to seek veterinary care at your vet or an ER clinic immediately. It is possible there is an injury, neruologic or muscular issue, illness, or other underlying problem that should be seen ASAP especially if it is causing disorientation and weakness.

These kittens may be suffering from fading kitten syndrome, or were born by a cat infected with FeLV. Since two kittens are already dead and the third kitten is showing signs, I suggest you take the remaining kittens to a veterinarian today, as this is an emergency. Sometimes supportive care can save them, however if they indeed suffer from one of these two diseases, there is a high mortality incidence. A veterinarian can examine and diagnose the problem and assess your kittens and hopefully treat them.

A full diagnosis would be required before any treatment could be recommended in such a severe case. A full physical exam by your vet will be essential to try and determine the cause of the paralysis but unfortunately, recovery would not be guaranteed. Fever, dehydration and viral or parasitic infections of the nervous system would all be concerns

Without an exam it would be hard to say what is wrong. If this is something he's had since birth, congenital issues such as cerebellar hypoplasia can sometimes cause symptoms like poor coordination, but the cats are otherwise happy, healthy and enjoy full lives. Other muscular or nerve issues, illnesses, or injuries may also cause coordination problems, so it is always a good idea to rule out any health issues with your vet that may be treatable.

Poor Kitten. This could be due to her lack of movement and playing. I would try to force her to get up and walk a little each day. You can try to make her take steps up and down small stairs if possible to help strengthen her legs. If there are any treats or canned food that she particularly likes, this may help to entice her. I would also try several different types of cat toys for her to play with. At her age, she should still be sleeping and eating majority of the time but her curious and playful side should start coming out. If you have any friends that have kittens around the same age, you may want to try to socialize them to see if this helps her as well. If she continues, I would have your vet look at her again to see if there are any additional problems that could be going on. I hope this helps!

She should be checked by a vet. This may be from an infection the mother had while pregnant known as cerebrellar hypoplasia or a developmental problem is she was small or the runt. If it just came on all of a sudden then her blood sugar may be low and it may need to be supplemented with karo syrup or nurtrical

Dragging the hind legs is not normal but they will stumble since they are learning to walk. Dragging the hind legs is concerning for a problem with brain development: https://www.petcoach.co/article/cerebellar-hypoplasia-in-kittens/ Other causes are also possible. I recommend to play it safe and have the kittens examined by the veterinarian. The vet should be able to determine if this is normal or pathological. I hope this helps and please feel free to post any additional questions.