My puppy accidentally ate Zeniquin antibiotic. What should I do?

A normal dose of Zeniquin is 2.75-5.5 mg/kg, and your puppy ingested 12.2 mg/kg. As an antibiotic, this medication may cause possible transient vomiting, diarrhea, or a loss of appetite. In young puppies given high doses of Zeniquin daily for 2-4 weeks, lameness and cartilage problems were noted in a study, but this would not be expected after a one-time ingestion. At this point, I recommend feeding a bland diet of boiled white meat chicken and white rice for the next few days to decrease stimulation to the GI tract. After a few days of this diet, you can gradually transition back to puppy food over another 5-7 days. If you need additional peace of mind, you can call the ASPCA animal poison control center at (888) 426-4435. Unless they direct otherwise, I cannot see any benefit in giving activated charcoal or other decontaminants after an antibiotic. I hope this helps and that all goes well!