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Can I use NexGard/Advantage after Capstar and with a spot-on?

Updated on September 23rd, 2025

Pet's info: Dog | American Staffordshire Terrier | Male | neutered | 2 years and 2 months old | 79 lbs

I gave my cats and dog capstar last night around 7pm my one cat threw up like half hour later but I plan on giving the cats advangtage ll and the dog nexgaurd at around 3pm today I was wondering should I give them another capstar before I give it to them also my dog has had hartzgaurd spot on flea and tick and had bath 2 day after but isn't working is it still ok to give him nexgaurd?

1 Answer

Most Helpful Answer

Jessica Keay, DVM

Answered By Jessica Keay, DVM

Veterinarian

Published on December 11th, 2019

Good morning! Capstar is generally thought to be effective for 24-48 hours, so I don't think you need to give another Capstar if you gave one last night. The nexgaurd should not interact negatively with the spot-on product or bath because they work differently. If you are having difficulty with fleas in your pets then you may also need to treat your home and possibly your yard. Vacuum all floors (including wood floors) and furniture and throw the contents in the trash outside, wash all pet pedding in hot water if possible and put in hot dryer. Then either have a professional treat your home or use a product like Knockout spray or fogger https://us.virbac.com/home/our-products/pagecontent/product-selector/kno/knockout-brand-products.html
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