My dog is nervous on Propalin for incontinence. Is this normal?

First of all i would recommend checking the dosage, it is written very clearly in the leaflet: 0.1 mL of Propalin Syrup per 5 kg of body weight, 3 times daily. this means he needs 0.16ml 3 times daily. unfortunately propalin doesn't always work, it does not surprise me because his case is not a classic case of urinary bladder atony which Propalin treats mainly.

I wish I had a little more information to help you with this question. IF she is just starting the medication and is on a loading dose then she could just be pretty drunk from the medication and may improve in time as her body adjusts. However, if she has been on the meds for a while and these are new changes then I would be concerned that this may be part of her underlying neurologic problem and not due to the meds. Regardless, I would encourage you to follow up with your veterinarian soon. In the meantime if you have other questions I would encourage you to request a consultation for more direct question and answer and “discussion” format. Best of luck and thank you for using Pet Coach.

I'm sorry you are dealing with this condition with Gizmo. Phenylpropanolamine often works well for urinary incontinence, but I am worried that there might be something else going on if Gizmo is drinking a lot of water. If there is another medical condition going on, Phenylpropanolamine may not work. So, I would have you veterinarian perform a urinalysis on Gizmo to check for any underlying medication conditions that may be causing the urinary incontinence that are treatable with a different medication. I have included a link to more information on Phenylpropanolamine as well below. The dosage can be variable for each dog, so I would ask your vet for a dosage recommendation if they think that is the right medication for Gizmo. https://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=614 Thanks for using PetCoach.

Phenobarbital is within a group of drugs known as barbiturates. The most common side effects in dogs, by far, are sedation, increased drinking, increased urination, and increased appetite. If the drugs were the cause of the behaviors you are witnessing, this would have to be classified as some sort of paradoxical reaction to the medication. In other words, it would be causing symptoms that are opposite to the purpose of the drug itself. Though I have not personally witnessed this, there are reports in rare instances of dogs becoming hyperactive and agitated after use of phenobarbital. While I can not say with certainty that this is the cause of the behaviors, It is definitely curious that they began at the same time as medication was started. You may want to speak with your vet about these observations and possibly choose a different medication.

Yes, this is a common side effect of this medication. Temaril-P contains prednisolone, which is a steroid - this is very effective at relieving allergy-related itching as well as a variety of other conditions, but it often causes increased thirst and urination as a side effect. In some dogs, this can be severe enough to cause urinary accidents in the house. This isn't dangerous at all, but can definitely be annoying for dog owners! I would recommend calling your veterinarian in the morning to let them know that Marley is having this problem. He/she may recommend reducing her dose to decrease the chance of further accidents.

Proin starts to be toxic at about 15mg/kg. Kobi ingested just over 6.8mg/kg and at that dose the most common side effects are mild hypertension (high blood pressure) and bradycardia (slow heart rate). Of course, every dog is different. I suggest you have Koji examined by your veterinarian especially if you are noticing any abnormal behavior. Other adverse effects can potentially be seen even at therapeutic doses. They include restlessness, urine retention, anorexia (not wanting to eat), tachycardia (increased heart rate), and hypertension (high blood pressure). Stroke-like signs have been reported rarely. Other rare clinical manifestations of toxicosis may include piloerection (hairs standing up on end), vomiting, tachypnea (fast breathing), anxiety or agitation, hyperthermia (increased body temperature), tachycardia, tremors, and potential seizures.

Anything all natural doesn’t have any drug interactions, so yes they can be given together. Unfortunately there is nothing natural that is proven to help with urinary incontinence in dogs. I would stick with the Propalin if it is working for Cruz and continue the natural supplement if you wish, since it won’t do any harm. I hope that Cruz does well with his medication. Best wishes and take care.