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My dog ate PROIN. Is it toxic? What symptoms should I expect?

Updated on September 23rd, 2025

Pet's info: Dog | Shiba Inu | Male | 8 months and 22 days old | 6 lbs

10 month old weighing 20 lbs just ate about 50mg of older dogs PROIN What can we expect to happen

1 Answer

Most Helpful Answer

Dr. Strydom, DVM

Answered By Dr. Strydom, DVM

Veterinarian

Published on October 9th, 2019

Proin starts to be toxic at about 15mg/kg. Kobi ingested just over 6.8mg/kg and at that dose the most common side effects are mild hypertension (high blood pressure) and bradycardia (slow heart rate). Of course, every dog is different. I suggest you have Koji examined by your veterinarian especially if you are noticing any abnormal behavior.

Other adverse effects can potentially be seen even at therapeutic doses. They include restlessness, urine retention, anorexia (not wanting to eat), tachycardia (increased heart rate), and hypertension (high blood pressure). Stroke-like signs have been reported rarely. Other rare clinical manifestations of toxicosis may include piloerection (hairs standing up on end), vomiting, tachypnea (fast breathing), anxiety or agitation, hyperthermia (increased body temperature), tachycardia, tremors, and potential seizures.
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