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Why did my cat foam at the mouth after taking anxiety medicine?

Updated on September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Male | unneutered | 1 year and 2 months old | 11.5 lbs

My cat is prescribed ear drops, and erythromycin ointment for conjunctivitis. He tolerates these medications well except for some drooling. Today I added fluoxetine, for anxiety. I have an oral solution and I gave 2.5 mg In 0.6 ml. The syringe I used, though new, was not of great quality and the medication was given in a burst (very fast like a spray). After this my cat darted off and began foaming at the mouth. This lasted only a period of minutes and my cat is now behacing normally. Thoughts?

1 Answer

Most Helpful Answer

Destini R. Holloway, DVM

Answered By Destini R. Holloway, DVM

Veterinarian

Published on July 21st, 2017

Foaming at the mouth in a cat after medication is typically a sign that the medication was either bitter tasting to them or it just wasn't pleasant. You can try the medicaiton again, giving it slowly this time and see what response Kitty has. If he foams again, then you can ask your vet if there is another flavor that you can get this medicaiton in, that is more tolerable for Kitty. Best wishes and take care.
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