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Should I use Vectra 3D or Frontline for flea and tick prevention?

Updated on September 23rd, 2025

Pet's info: Dog | Cockapoo | Female | spayed | 10 years and 1 month old | 20 lbs

I am looking for a professional opinion. What do you think is better for flea and tick killer and prevention? Vectra 3D or FrontLine?

2 Answers

Most Helpful Answer

Answered By David Darvishian

Veterinarian

Published on August 30th, 2017

Hi and thanks for using Petco Pet Education Center, formerly Petcoach! In my opinion and that of many of my class mates is that Frontline is starting to fail and all of us are seeing flea infestation breakthroughs from it. It personally happened to all of my pets over one year ago. I used Frontline for years without problems then the summer of 2016 changed. All 3 dogs and one cat had flea problems. I went to another product (Bravecto) and the problem dissolved after one dose so I know it wasn't some horrible environmental problem. I like Vectra 3D because it has a repellent nature to it. It is becoming increasing important for heartworm protection also since it can repel mosquitoes. We are starting to see heartworm resistance in the gulf states and it's not that people are giving the heartworm pills. There is actual resistance in some mosquitoes to heartworm pills and pairing the heartworm pills up with a topical flea/tick with repellent characteristics is being advised in the deep south to combat the problem. So yes, Vectra 3D is a good product. Good luck with Dolce. Hope this helps.

2Pet Parents found this answer helpful

Related Answers from Veterinarians

Answered By David Darvishian
Veterinarian
Hi and thanks for using Petco Pet Education Center, formerly Petcoach! In my opinion and that of many of my class mates is that Frontline is starting to fail and all of us are seeing flea infestation breakthroughs from it. It personally happened to all of my pets over one year ago. I used Frontline for years without problems then the summer of 2016 changed. All 3 dogs and one cat had flea problems. I went to another product (Bravecto) and the problem dissolved after one dose so I know it wasn't some horrible environmental problem. I like Vectra 3D because it has a repellent nature to it. It is becoming increasing important for heartworm protection also since it can repel mosquitoes. We are starting to see heartworm resistance in the gulf states and it's not that people are giving the heartworm pills. There is actual resistance in some mosquitoes to heartworm pills and pairing the heartworm pills up with a topical flea/tick with repellent characteristics is being advised in the deep south to combat the problem. So yes, Vectra 3D is a good product. Good luck with Dolce. Hope this helps.
2Pet Parents found this answer helpful

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