Two Easy Ways to Start Earning Rewards!
Earn 2X Pals Rewards points at Petco
when you use Petco Pay!
Updated on September 23rd, 2025
Pet's info: Dog | Newfoundland | Female | unspayed | 3 months and 25 days old | 50 lbs
How long should a 4 month puppy be off of an antibiotic prior to a urine culture? We are visiting a specialist for an UTI after three courses of antibiotics.
4 Answers

Answered By Dr. Heidi DVM, CVA, CCRT, CVTP, CVSMT, CVCH
Veterinarian, Certified Veterinary Acupuncturist, Certified Canine Rehabilitation Practitioner
Published on February 23rd, 2018
Answered By Angel Alvarado, LVT
Licensed Veterinary Technician
Published on November 9th, 2017
You should begin to see some improvement in symptoms after a few days IF the bacteria responsible is sensitive to the antibiotic. Ideally, a sterile urine sample should be collected and submitted for urinalysis and a urine culture/sensitivity panel. This second test should be able to identify the organism responsible as well as the most effective antibiotic to use in treatment.
1Pet Parents found this answer helpful
Answered By Dr. Elizabeth
Veterinarian
Published on November 19th, 2019
It is generally expected that the antibiotics will kick in and the clinical signs should subside by day 5. I would be concerned there is antibiotic resistance, a bladder stone or bladder cancer causing the continued symptoms but it could also just be a slow response. I recommend to call you vet and decide what to do next. Best of luck and please feel free to post any additional questions.
1Pet Parents found this answer helpful
Answered By Andrea M. Brodie, DVM
Veterinarian
Published on August 19th, 2018
It can take up to six weeks of taking antibiotics to combat a UTI. You will need to be patient. 4 days of treatment is a very short time and you will likely not see any results for another few days. Make sure he drinks a lot, and go for walkies and the more often he urinates, the better, as he is getting rid of bacteria in his bladder.
1Pet Parents found this answer helpful