My 45lb dog needs Trifexis. Can I use a larger tablet or cut it?

I don't recommend breaking these pills in half. Due to the manufacturing process, we can't guarantee that the drug is evenly distributed in the pill. So by giving half, you could be giving all or none of the active ingredients. It would be best to have the appropriate prescription for Rose.

Hi there. Trifexis has a very wide margin of safety (a dog could eat an entire box and not have any serious issues, in most cases), so it's unlikely that this will cause any problems. The most likely side effect would be vomiting or GI upset, in the first day or two after taking the meds. If she's acting normal so far, you probably won't see any issues at all. It's fine for her to continue with her normal daily routine as far as eating, exercising, etc.

Definitely get PYY the smaller size. It's never recommended to try to cut a larger dose of the medication in half because you could either under dose your dog, or accidentally overdose them. I hope this helps!

So this medication contains a combination of Spinosad and Milbemycin. Milbemycin is used in dogs as a heartworm prevention, and can safely be given at two to four times the normal dose used for heartworm prevention. Spinosad is used for flea prevention, and it is a relatively safe drug. The most common side effects seen with its use include a decreased appetite, diarrhea, vomiting, and lethargy. Studies on research dogs showed no long term effects on dogs that were given ten times the recommended dose. More than likely, Molly will be just fine, but if you see any of the side effects that I mentioned above, have her seen by a vet just to be safe. Best of luck, I hope this helps!

With medications in tablet form, you can certainly cut them in half and still be sure that you are giving half of the medication. Unfortunately with chewable medications (like Nexgard, Heartgard, etc.), splitting a dose in half does not ensure that half of the medication will be given. The active ingredients are mixed throughout the chews, but not necessarily in a uniform way. To answer your question, no, you shouldn't give Frosty half of a Nexgard. Instead, see if you can exchange the product for the correct size. It's likely that your vet will be able to prescribe a single dose while you sort out the exchange process. I hope that everything goes well!

Toxic reactions of the main ingredient in Trifexis in dogs starts at 400mg/kg. Assuming duke had 6 tablets of 60-120lbs he had a little under 10,000 mg, for his weight toxic dose starts at 12,000 mg, so he should be safe, but if you start seeing worse symptoms or if he isn't better by tomorrow morning- take him to the vet in order to get it checked.

Thank you for submitting your question regarding Sophie. First, you need to ensure the flea medication is labeled for use in puppies. Second, if you do not give medication for the correct weight, it will likely be ineffective. If she already weighs 30 pounds and the medication only covers up to 25 pounds, you will be under dosing her. I hope this information helps!