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When can I safely use Simparica after Frontline Plus for fleas?

Updated on September 23rd, 2025

Pet's info: Dog | Chihuahua (Smooth Coat) | Male | neutered | 9 lbs

Can you use Simparica with Frontline plus or should I wait until the end of Frontline Plus skin dosing ? At three weeks post Frontline dose now, moved to a condo with a dog park and fleas are a problem

1 Answer

Most Helpful Answer

Destini R. Holloway, DVM

Answered By Destini R. Holloway, DVM

Veterinarian

Published on October 4th, 2019

You can safely use one after the other if you wait at least 2 weeks in between applications. So since it has been 3 weeks, then you are ok to switch to Simparica now.

I would also recommend treating the condo with a flea fogger purchased from your local Home Depot or Lowe's.

Thanks for visiting Petco Pet Education Center, formerly Petcoach and I hope that you get rid of your flea problem soon! Take care.
Vote Icon16Pet Parents found this answer helpful

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