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My cat still has fleas after Frontline. Can I use Advantage II now?

Updated on September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Male | neutered | 1 year and 5 months old | 14 lbs

Have a bad flea infestation. Used Frontline last week on 14lb cat. Combed dozens of fleas today. OK to also use Advantage II for large cats?

1 Answer

Most Helpful Answer

Vanessa Yeager DVM MPH

Answered By Vanessa Yeager DVM MPH

Veterinarian

Published on September 27th, 2017

Hi and thanks for your question.

Yes, advantage 2 large cat can be used but not after frontline was just applied last week. Frontline is indicated for a month, so I would wait another 3 weeks until administering the Advantage 2 large cat. You run the risk of overloading her system otherwise.

I hope this helps and thanks for using Petco Pet Education Center, formerly Petcoach!
Vote Icon1Pet Parents found this answer helpful

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