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Is it okay to give my dog lisinopril instead of enalapril for a dose?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Female | 20 lbs

Can I substitute Lisinopril for enalapril for 1 dose? Web says yes but would like an expert to advise

2 Answers

Most Helpful Answer

Dr. Andrea

Answered By Dr. Andrea

Veterinarian

Published on June 10th, 2018

I would not recommend that you change out meds without direct supervision by your vet. Dosing is not the same between these two drugs and it depends a lot on what condition we are treating here. Lisinopril is not as commonly used in dogs.
If you are out of meds and cannot refill until tomorrow, it would be better to skip a dose then to change meds suddenly (although certainly skipping meds is not advised if you can avoid it).
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Related Answers from Veterinarians

  • Answered By Lauren Kennedy, DVM

    Veterinarian

    Published on March 8th, 2018

    Enalapril is the generic form of this medication and it is the same as the enalapril used in humans. Lasinopril is a similar drug, is in the same class, and has a similar mode of action. Ofterntimes it is doctor preference which one is prescribed but occasionally there are reasons to choose one over the other. Enalapril is more commonly used in veterinary medicine.

    So yes, you could potentially switch to lasinopril but I would definitely speak with the prescribing veterinarian first to make sure there are no specific reasons to avoid it.

    I hope this helps. Thanks for using Petco Pet Education Center, formerly Petcoach. Best of luck.

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    1Pet Parents found this answer helpful

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