My dog is lethargic after Frontline Plus. Is this a medical concern?

it may be a reaction to the medicine. The best thing to do is bathe him in dawn dish washing liquid to strip the medicine and oils from his coat and skin. If he starts twitching or having tremors, then he needs to go to a vet. If he is not normal by morning then I would take him in to see if there is something else going on

If Lilith ingested Frontline, there isn't much you can do for her at home unfortunately. She really needs to be seen by a veterinarian. They will at the very least give her some fluids to help hydrate her and flush the substance out. She may also need more treatments such as blood work and medication.

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Foot foot. I'm sorry she hasn't been well! So cats are very sensitive to flea treatments, and her symptoms seem to match up with flea treatment toxicity (except for urinating outside the litter box). It may be that the Frontline is causing her problems. I would wash off the Frontline now, give her a bath to get it off if you applied it within the last 24 hours. If it's been more than 24 hours, have her seen by a vet now. Depending on when you applied the Fronline, either wait a week (if the Frontline was applied in the last 24 hours) or two weeks since the application (if apply longer than 24 hours ago), then use a different flea treatment program like Revolution or Advantage. I would not use Frontline again. As for urinating outside the box, this could be due to feline idiopathic cystitis. Stress can bring this on, and a reaction to flea treatment can be stressful. Have her seen by a vet for this. I hope this helps!

Poor Ember! Vomiting and lethargy are both common side effects of Trifexis, and do not usually indicate any kind of serious problem. But, you could certainly opt to use a different flea and heartworm medication for her in the future to avoid this issue. For tonight, I would withhold food and leave her alone to rest since she doesn't feel well. If she's still acting noticeably lethargic tomorrow, or if she develops any other symptoms, then I would call your veterinarian or take her in for a check-up to make sure nothing else is wrong.

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Luna. It's ok that you put the topical flea medication on her. You can see some lethargy after a vaccine, and she should be back to normal by tomorrow. I hope this helps!

I agree, it's impossible to know if this is unrelated (symptoms like this could be due to a compressed disc in the spine or cranial abdominal pain) or a reaction to the flea medication. I recommend to play it safe and have Harvey examined by the veterinarian. The doctor will likely get an idea of pain or skeletal abnormality from the physical exam. You may also wash him in Dawn dish soap to remove the flea product just in case. Be very gentle when handling him. I hope this helps and please feel free to post any additional questions.

There are several tick-borne diseases that could cause lethargy. These include lyme disease, rocky mountain spotted fever, ehrlichiciosis and anaplasmosis. If your dog is lethargic, a visit to your vet is recommended. They can perform a good physical exam and may recommend bloodwork including testing for these tick-borne diseases. It is possible the lethargy could be related to the tick, but there are also many other possible causes for lethargy. An exam and bloodwork will help us narrow down the possible causes.