Is 500mg Doxycycline 3x daily too high for my dog with lupus?

Hello and thank you for contacting Petco Pet Education Center, formerly Petcoach. The recommended dose of doxycycline for Lyme disease is 20mg/lb once daily, so Joey should be taking around 200mg a day. Rarely doxycycline is used at higher doses or more frequently than once every 24hrs. Please, get in touch with your local vet to discuss the treatment as it sounds that the dose should be slightly adjusted.

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! The maximum dose of doxycycline is 10mg/kg twice daily (or 20mg/kg/day). If you gave Chylo around 33-35mg that is 20mg/kg and he should be fine. Do not give him any more for 24 hours. Doxycycline is very hard on the stomach so he may have vomiting. I hope this helps and have a great day!

Hello and thank you for your post! With Ehrlichiosis I typically dose at 5mg/kg every 12 hours, which equates to roughly 200mg twice daily. The 100mg dose does seem a bit low. I typically treat for about 6 weeks as well. Based on cases your vet has seen, he / she may have a reason for dosing at the 100mg twice daily. That is what I treat Ehrlichiosis with though and is effective. If you have any other questions please feel free to contact me. I am also available via consultation.

Thank you for using Petco Pet Education Center, formerly Petcoach! I actually typically recommend that doxycycline is given twice daily and it has been effective. I recommend calling your vet to make sure that the total dosage is correct and that Uzzi is still receiving the correct amount per dose. You should also let your vet know of any side effects you are seeing as they may consider a shorter course, changing antibiotics, or adding probiotics. I hope this helps and that Uzzi feels better soon!

Thanks for using Petco Pet Education Center, formerly Petcoach! My fist recommendation would be to call the vet to double check because amoxicillin has a very broad dose range. This is a little bit higher dose than I usually use but may be exactly what your vet wanted. (I would do about 2 cc’s twice daily for most patients her size.) There is not much harm in higher dosing, other than an increased risk of nausea, vomiting, and diarrhea so don’t worry about poisoning Lupita. Twice daily dosing for the amoxicillin is definitely correct as this drug needs to be in the bloodstream for a sustained time to work properly. The prednisone dose is fine. Hope this helps and best of luck to you and Lupita!

It is normally fine to adjust the dosing schedule by two hours or so as needed. However, I legally cannot reccomend a change in medication, without having established a client-doctor relationship with you. I will have to refer you to your vet to answer this question. They should be happy to answer a quick question like this if you give them a call. I hope that helps and all is well with Dixie.

A part from possible oesophageal inflammation, Prince should not experience any other side effect a part from nausea, vomiting, and possibly diarrhea. I would not be extremely worried and just monitor him at this stage. Should you notice any signs listed above, a check up would be needed.