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Why do vets give diltiazem every 8 hours instead of the 12-hour pill?

Updated on September 23rd, 2025

Pet's info: Dog | Wolf Hybrid | Male | neutered | 6 years and 9 months old | 110 lbs

Why do vets prescribe diltiazem every 8 hours when there is diltiazem extended release they could take every 12 hours?

1 Answer

Most Helpful Answer

Answered By Linda G, MS, DVM

Veterinarian

Published on January 14th, 2020

Hello. The reason for not always using an extended release product really falls to the type of heart failure is being treated. Most cardiologists do prefer the prompt release product given every 8 hours. But in cases of ventricular rate control in atrial fibrillation, the extended-release diltiazem administered every 12 hours is very effective, especially when combined with digoxin. If it is difficult to reliably administer Dakota's medication every 8 hours, please discuss this with your veterinary cardiologist to see what will work out for you & your pet. Thanks for using Petco Pet Education Center, formerly Petcoach.

1Pet Parents found this answer helpful

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