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My cat is acting strange and lethargic after Bravecto. Is it serious?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Female | spayed | 2 years and 10 months old | 7 lbs

I administered a dose of Bravecto to our cat about 8 hours ago. She has been acting strange, trying to lick at the area (i don't believe she is able to reach it), lethargic and will not let me near her. She always wants me to play and pet her. This is abnormal behavior and I am trying to discern whether she needs emergency care or if this will just pass. The flea treatment was given to me by our vet, which is closed now and it was a sample to try on her.

1 Answer

Most Helpful Answer

Ricardo Fernandez, DVM

Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on November 29th, 2017

Thanks for using Petco Pet Education Center, formerly Petcoach! This could be due to the area feeling different after application of the Bravecto. There are possible reactions associated with any medication or preventative product given to an animal though this would be an unusual reaction to a topical flea preventative like Bravecto. If the skin around at the site it was administered looks normal (not irritated or inflamed) and she is otherwise doing well, I would continue to watch her for now and have her evaluated by your veterinarian tomorrow if no improvement. If she appears to be too different to what she normally is, have her evaluated tonight to ensure she is not having an unusual reaction to the Bravecto. I think she is likely reacting to the application of the product because she can feel something in her skin that she is not used to rather than having a complication. I understand your concern and I hope that she starts acting more like herself quick. Good luck!
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