Is mirtazapine safe for my pet's blood pressure with amlodipine?

Mirtazipine is typically well tolerated in dogs. You may see sedation or drowsiness. Symptoms that should be addressed by your vet include low blood pressure or increased heart rate. Given his age, you may want to have him checked out at the nearest veterinary ER or put a call in to the Pet Poison Helpline ( (855) 764-7661 ). There is a fee for this call, but they will have toxicologists and doctors who can tell you definitively if Cody is at any risk.

Mirtazipine can cause serotonin syndrome which is characterized by hyperactivity, muscle tremors, vocalization and behavior changes. This is more likely at high doses but has been reported to occur at typical doses as well. It is cleared through the kidneys so a dose reduction is typically recommended for cats with decreased kidney function. Megacolon should not be a concern.

Hi there, and thank you turn your question. Yes, it should be fine to administer amlodipine and methimazole at the same time. I hope this helps, and that Ginger Grace is doing well in her medications!

Mirtazapine does have a side effect of drowsiness or sedation in pets. It is commonly used in cats as an appetite stimulant. 30mg would be 4 times higher than I normally use, and this overdosage can cause: 57% vocalizing, 38% agitated, 23% vomiting, 21% tachycardic, 15% ataxic and 11% lethargic. The symptoms can last a little longer than 72 hours. As long as Dolly is still eating and drinking normally, I would continue to watch her. If the she is still not completely normal in a day or two, she may need a checkup with a vet.

The dosing does go up to 1mg/kg every 12 hours. So Angel's dose at this would be 20mg twice daily, so she should be absolutely fine. I hope this helps! Please let me know if you have any further questions or concerns and I would be more than happy to help you further.

Hello, thank you for using Petco Pet Education Center, formerly Petcoach. There are no known contraindications with using mirtazapine and cisapride together but remember, all cats react differently to medications so if you notice any abnormal issues then stop the medications immediately and call your vet. Hope this helps. Best wishes.

Mirtazipine usually only stays in their system for 24-72 hours dependent on how high the dose was. If he was being dosed daily it likely was a small dose and will only be effective for approximately 24-36 hours. I would talk to your vet about continuing it. If they haven’t figured it why he isn't eating, then they may recommend additional diagnostics like blood work or X-rays. If you already know then you can continue mirtazipine longer until he is feeling better. And yes, he may have developed a preference for the tuna juice. You can continue to add tha to his other food. I hope this helps.