Is Mirtazapine safe for cats with kidney disease and megacolon?

Hello, thank you for using Petco Pet Education Center, formerly Petcoach. There are no known contraindications with using mirtazapine and cisapride together but remember, all cats react differently to medications so if you notice any abnormal issues then stop the medications immediately and call your vet. Hope this helps. Best wishes.

Mirtazapine does have a side effect of drowsiness or sedation in pets. It is commonly used in cats as an appetite stimulant. 30mg would be 4 times higher than I normally use, and this overdosage can cause: 57% vocalizing, 38% agitated, 23% vomiting, 21% tachycardic, 15% ataxic and 11% lethargic. The symptoms can last a little longer than 72 hours. As long as Dolly is still eating and drinking normally, I would continue to watch her. If the she is still not completely normal in a day or two, she may need a checkup with a vet.

I would not give her morphine without seeing a vet as this can cause major respiratory depression and severe nausea. Also without seeing if she is healthy for morphine, it could make her get worse. The mirtazapine can be given for an appetite stimulant but cats can only tolerate 3.75mg (1/4 tablet of a 15mg mirtazapine) every 72 hours. If at all possible, I would strongly consider having a vet take a look at her to see if there is anything else they can do for her and to figure out why she isn't feeling well. I hope this helps.

Mirtazapine is safe to use with amlodipine. Mirtazapine at high doses could potentially decrease blood pressure, but at typically prescribed doses, it is safe to give with amlodipine. Your vet may want to monitor blood pressure a few days after starting the mirtazapine just to be sure its all looking good. Thanks for asking Petco Pet Education Center, formerly Petcoach!

Mirtazipine usually only stays in their system for 24-72 hours dependent on how high the dose was. If he was being dosed daily it likely was a small dose and will only be effective for approximately 24-36 hours. I would talk to your vet about continuing it. If they haven’t figured it why he isn't eating, then they may recommend additional diagnostics like blood work or X-rays. If you already know then you can continue mirtazipine longer until he is feeling better. And yes, he may have developed a preference for the tuna juice. You can continue to add tha to his other food. I hope this helps.

Poor girl! Yes you can safely give Cerenia and Buprenorphine on the same day and even at he same time, if needed. If she has kidney disease then subcutaneous fluids will also help with that. I know th Cerenia helps with her vestibular disease because it mostly is helping with her nausea. However Cerenia is only safe to give for 5 consecutive days. After that time frame I would suggest asking your vet for motion sickness medication (Dimenhydramine) that can be given long term, if needed. I hope your kitty feels better soon!

Thanks for using Petco Pet Education Center, formerly Petcoach. I'm sorry to hear Katniss has been ill. Cerenia is an anti-nausea medication. Animals with vestibular disease often feel "motion sick" - having something similar to vertigo. So this is great for that. It also helps settle the stomach which helps with appetite. Mirtazapine is a true appetite stimulant. Even with both of these, the balance apparatus is very mad and so falling over may still happen. I recommend bringing slightly warmed wet food to his face a few times daily to encourage eating. If no improvement in the vestibular signs within a week, I recommend a CT scan of the head to look for inner ear infection or, heaven forbid, a tumor. Vaseline is ok for paw pads, though olive oil or coconut oil is even better. To be honest, most cracked paw pads are not painful and do not need treatment. I'd recommend an over the counter laxatone product for the hair balls, along with frequent brushing. Omega 3 fatty acid supplements can help with the dandruff. Best wishes to you and Katniss.