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My cat has cancer & kidney disease. Is doxorubicin safe to use?

Updated on September 23rd, 2025

Pet's info: Cat | American Shorthair | Male | 13 lbs

My cat was diagnosed with a tumor in his intestines and swollen kidneys with a 3.1 creatinine. He has been on chemo for the past 3 weeks and his tumor shrunk a lot, his creatinine levels went down to 2.6, he's also been anemic but on iron vitamins. Now the Doctor wants him to take doxorubicin this week, having read all the horror stories on how it's not safe on a cat's kidney, I have conflicted emotions. How safe is doxorubicin at a low dosage? Does the risk outdo the outcome( remission).Thanks

1 Answer

Most Helpful Answer

Dr. Leigh, DVM

Answered By Dr. Leigh, DVM

Veterinarian

Published on October 5th, 2017

Doxorubicin is a very effect chemotherapy drug but, with all medications, there can be side effects. Since your vet knows your cat's entire medical history, he/she is the best person to guide you with advice on the best treatment regime for your cat. I am assuming that your vet believes that this drug is needed to help treat your cat's cancer and the benefits outweigh any risks associated with the drug. Your vet will need to monitor his kidney values closely for any changes while taking the drug and discontinue, if needed. So sorry that your cat has a tumor and I really hope that he goes into remission.
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