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Updated on September 23rd, 2025
Pet's info: Farm Animal | Horse | Male | neutered | 12 years and 9 months old | 8 lbs
I have a cat with CKD. He also has anemia and was prescribed darbepoetin. He weights 4kg and I was told to give him 4mcg twice a week. That is a total of 8mcg a week which seems a little too much compared with the guidelines I was able to find on the Internet. Any advice would be appreciated, I haven't started the treatment yet.
2 Answers

Answered By Vanessa Yeager DVM MPH
Veterinarian
Published on October 2nd, 2017
Answered By Dr. Heidi DVM, CVA, CCRT, CVTP, CVSMT, CVCH
Veterinarian, Certified Veterinary Acupuncturist, Certified Canine Rehabilitation Practitioner
There is a huge variation in the recommended doses for darbepoetin for cats without research to prove that one dose is better than another. The general range is 0.25 mcg/kg up to 1.25 mcg/kg. Most people start somewhere in middle at 0.45 mcg/kg. So, if Rysiek is 4 kg, then 4 mcg is a reasonable dose, but I have not had to give it more than once a week because it generally works quite quickly. I think it would be reasonable to give one injection, then check his red blood cell count a week later to see what his response has been and adjust it from there. If you're not comfortable with that, please contact your veterinarian and discuss it with them. They would certainly want to make sure what you are comfortable with the treatment plan for Rysiek.
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