Why did my cat vomit after Doxycycline? She's tired and not eating.
Thanks for using Petco Pet Education Center, formerly Petcoach. I’m so sorry to hear about Misty. If the medication had caused the vomiting, I would have expected it to cause vomiting days ago when you started it.
That leads me to believe it is less likely related to the medication and more likely related to something else.
That being said, double check that you are giving the correct amount and do shake the bottle well each time you give it.
Just like in people, there are dozens of reasons vomiting occurs including: infection, dietary indiscretion (eating that piece of plant or human food, or dead mouse), GI foreign body (eating that hair band which is now causing problems), toxin, non specific nausea, diet change or new treat, and the list goes on.
If it was just the three times in a row, I would just withhold food and water for 2 hours, then reinteoduce water. If she holds that down well, offer a small bit of food 8-12 hours after the last episode of vomiting. Don’t repeat tonight’s dose of medication.
I am concerned in the back of my mind that something else is going on since her appetite had started decreasing. Is it related to the disease we are treating with the doxycycline or some other problem?
Certainly if the vomiting continues or she is not ready to eat in the next 24 hours, or you see any new signs, please head to your vet or an emergency vet for re-valuation.
Best wishes to you and Misty!
Updated on September 23rd, 2025