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Published on November 8th, 2018
Updated on June 18th, 2026

Written by Dr. Nicole Vumbaco, DVM

Given the growing popularity of sugar-free foods, you have likely heard of xylitol. While this artificial sweetener offers many health benefits to humans, it is highly toxic for pets.
Given the growing popularity of sugar-free foods, you have likely heard of xylitol. While this artificial sweetener offers many health benefits to humans, it is highly toxic and potentially deadly for pets. Research indicates that xylitol toxicity in animals can occur at very low doses—sometimes less than one stick of gum.
Upon ingestion, xylitol can cause a severe drop in your pet’s blood sugar levels. In dogs, xylitol stimulates the pancreas to secrete excessive amounts of insulin, which causes hypoglycemia (low blood sugar) to occur.
Clinical signs may include:
Depending on the amount ingested, animals can even suffer life‑threatening liver damage.
Like most toxins, the effects of xylitol are dose-dependent and can be treated successfully if caught early. If you suspect ingestion, seek veterinary care immediately. Quick intervention is crucial for recovery.
Being proactive is key to protecting your pets—what’s sweet for us is not always sweet for them! Here are some common consumer products where xylitol may be hiding:
Gum is notorious for containing xylitol. Amounts differ from brand to brand, but in some cases, one stick of sugar-free gum can be lethal. Mints, candy and chocolate contain the substance as well. Never let your pet have access to these products.
Oral care and personal hygiene products are among the most common — and most overlooked — sources of xylitol in the average household. Because these items sit on bathroom counters, in purses, or in nightstand drawers, they're far more accessible to a curious dog or cat than most pet parents realize.
Xylitol is a go-to ingredient in human oral care because it actively discourages the bacteria that cause tooth decay. That makes it appealing to manufacturers — and makes the following product categories worth knowing by name:
| Product Category | Common Examples | Xylitol Risk Notes |
|---|---|---|
| Toothpaste | Spry, Tom's of Maine, Arm & Hammer (human formulas) | Often high concentration; a small squeeze can be dangerous to dogs https://www.aspca.org/pet-care/animal-poison-control |
| Mouthwash & oral rinses | ACT, Listerine Total Care variants | Liquid form is easy to lap up if spilled or left in a cup |
| Breath strips & breath mints | Listerine PocketPaks, Ice Breakers Duo strips | Highly concentrated in a tiny, palatable package |
| Breath sprays | Binaca, Dentyne spray | Small bottles are easy to knock off a counter and chew open |
| Chewing gum | Trident, Orbit, Ice Breakers, Pur gum | Gum is frequently left in bags or low pockets within a dog's reach |
| Nasal sprays | Some saline/moisturizing sprays | Less common but worth checking the label |
Always read the ingredient label. Xylitol may also appear under the name "birch sugar" or "wood sugar" on some product labels.
The danger isn't just what these products contain — it's how they're stored and how they smell. Flavored toothpastes and minty breath strips can smell appealing to a dog, who may chew through packaging to get to them. Even a small amount of xylitol from a single piece of gum or a partial tube of toothpaste can cause a serious toxic response in dogs, according to the ASPCA Animal Poison Control Center https://www.aspca.org/pet-care/animal-poison-control.
Cats are generally less likely to seek out sweet-tasting items, but they can still be exposed if a product spills or if they groom themselves after walking through a contaminated area https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information.
Never use human oral care products on your dog or cat. Human toothpastes — including "natural" mint varieties — are formulated for people who spit and rinse. Dogs and cats swallow what goes in their mouths, which means even a xylitol-free human toothpaste can contain fluoride or other ingredients that aren't appropriate for pets https://www.aspca.org/pet-care/animal-poison-control.
Always choose toothpastes, rinses, and dental gels that are specifically formulated and labeled for dogs or cats. You'll find a range of pet-safe dental care options at Petco.
If you're ever unsure whether a product your pet got into contains xylitol, bring the packaging with you to the vet — or read the ingredient list aloud to the poison control specialist. Speed matters.
Many pet parents are surprised to learn that xylitol shows up not just in food, but in the medicine cabinet. Both prescription and over-the-counter (OTC) medications are increasingly formulated with xylitol as a sweetener — making them palatable for humans but potentially dangerous for dogs in your household.
Specific product categories to check carefully include:
Always read the inactive ingredients list, not just the active ingredients, when storing any medication in a home shared with pets.
Even a small amount of xylitol can trigger a life-threatening response in dogs. When a dog ingests xylitol, the compound is rapidly absorbed into the bloodstream, where it causes the pancreas to release a large surge of insulin — far more than the ingested amount would warrant. This drives blood sugar to dangerously low levels, a condition called hypoglycemia https://www.aspca.org/pet-care/animal-poison-control.
Clinical signs to watch for include:
Depending on the dose, xylitol ingestion can also cause acute liver failure — a separate and equally serious consequence that can develop even when hypoglycemia is managed https://www.aspca.org/pet-care/animal-poison-control. Like most toxins, xylitol's effects are dose-dependent, and early veterinary intervention significantly improves outcomes. If you suspect your dog has ingested any product containing xylitol, contact your veterinarian or the ASPCA Animal Poison Control Center immediately — do not wait for symptoms to appear.
Current research on xylitol toxicity in cats is limited. Some veterinary toxicologists speculate that cats are less frequently exposed simply because they are more selective about what they eat. Others suggest that differences in feline metabolism may play a role in the lower number of confirmed toxicosis cases. Regardless, the absence of extensive case data does not mean cats are safe — the conservative and correct approach is to keep all xylitol-containing products, including medications, completely out of reach of every pet in your home https://www.aspca.org/pet-care/animal-poison-control.
Xylitol turns up in a wide range of pantry staples and specialty foods — often in products that pet parents use directly with their pets, like peanut butter for pill pockets or canned pumpkin for digestive support.
| Food Category | Common Examples |
|---|---|
| Baking ingredients | Granulated xylitol, xylitol-sweetened baking mixes |
| Baked goods | Sugar-free cookies, muffins, cakes, brownies |
| Nut butters | Certain brands of peanut butter and almond butter |
| Dairy and frozen treats | Some yogurts, ice creams and frozen desserts |
| Condiments and spreads | Sugar-free jams, jellies, syrups and honey blends |
| Protein products | Protein powders, bars and meal-replacement shakes |
| Beverages and flavorings | Water-flavoring packets and drink mixes |
Peanut butter and canned pumpkin deserve special attention. Both are popular tools for giving dogs medication or supporting digestive health — but some brands of each now include xylitol. Always verify the ingredient label before purchasing, and choose brands that are explicitly xylitol-free https://www.aspca.org/pet-care/animal-poison-control.
When shopping for dog-appropriate foods and treats, look for products formulated specifically for pets. Browsing dog food options at Petco makes it easier to find products that meet pet-safe ingredient standards.
Xylitol is valued in personal care formulations for its moisture-retaining and antimicrobial properties, which means it appears in products you may not think to keep away from pets:
While the concentration of xylitol in personal care products is generally lower than in food or medication, these products can still pose a risk — particularly if a curious dog chews on a tube, licks a wipe or gets into an open container. Store all personal care products securely, just as you would any medication https://www.aspca.org/pet-care/animal-poison-control.
Edible marijuana products intended for human use may contain xylitol as a sweetener. If you live in a state where cannabis edibles are legal and accessible, treat them with the same caution as any other xylitol-containing food — stored completely out of your pet's reach.
Pet-marketed CBD products generally should not contain xylitol, but formulations vary by brand. Always consult your veterinarian before introducing any CBD product into your pet's routine, and review the full ingredient list carefully before use.
There is not much research available on cats and xylitol. Some speculate that cats are simply pickier about what they eat and are therefore less likely to be exposed. Alternatively, the lack of confirmed cases of xylitol toxicosis in cats may have something to do with their metabolism. However, as we’ve seen with dogs, exposure to xylitol can be deadly. Therefore, the recommendation remains to keep xylitol out of reach from all furry friends, including cats.
The table below maps the most frequently reported xylitol-containing product categories to their typical risk level for dogs and cats. Use it as a quick reference — and always read ingredient labels before letting your pet anywhere near a human product.
| Product Category | Common Examples | Xylitol Risk Level | Notes for Pet Parents |
|---|---|---|---|
| Sugar-free gum | Trident, Ice Breakers, Orbit, Pur | Critical | Even one stick can trigger hypoglycemia in a small dog https://www.aspca.org/pet-care/animal-poison-control |
| Sugar-free candy & mints | Breath mints, hard candies, chocolate-flavored sweets | Critical | Concentration varies widely by brand; treat all sugar-free candy as high-risk https://www.aspca.org/pet-care/animal-poison-control |
| Baked goods & baking ingredients | Muffins, cookies, protein bars, xylitol sold as a baking sweetener | Critical | Baking-grade xylitol is highly concentrated; a small amount of dough or batter is dangerous |
| Peanut butter & nut spreads | Select store-brand or "natural" peanut butters | Critical | Commonly used to hide medication — always verify the label is xylitol-free before use https://www.aspca.org/pet-care/animal-poison-control |
| Oral care products | Toothpaste, mouthwash, breath sprays, breath strips, nasal sprays | High | Human toothpaste should never be used on pets; use only formulas made specifically for dogs or cats https://www.aspca.org/pet-care/animal-poison-control |
| Prescription & OTC medications | Chewable vitamins, liquid medications, sleep aids, some antihistamines | High | Xylitol is used as a sweetener in many chewable and liquid formulas; check every label https://www.aspca.org/pet-care/animal-poison-control |
| Condiments, syrups & spreads | Jams, honey products, flavored syrups, salad dressings | Moderate | Less common but increasingly present in reduced-sugar or "diet" versions |
| Yogurt, ice cream & dairy products | Low-fat or sugar-free yogurt, frozen desserts | Moderate | Plain, unsweetened yogurt is generally lower risk, but always confirm no xylitol is listed |
| Protein powders & water-flavoring packets | Drink mixes, electrolyte packets, meal-replacement shakes | Moderate | Sugar-free sport and diet products frequently use xylitol as a sweetener |
| Health & beauty products | Lip gloss, shampoo, sunscreen, baby wipes, personal lubricants | Moderate | Typically lower concentrations, but still potentially toxic — keep out of reach https://www.aspca.org/pet-care/animal-poison-control |
| CBD & cannabis edibles | Human-marketed gummies, tinctures, infused foods | Moderate | Pet-specific CBD products should not contain xylitol, but always consult your veterinarian before use https://www.aspca.org/pet-care/animal-poison-control |
How to read the risk levels:
If your pet has ingested any product from this table, contact your veterinarian or the ASPCA Animal Poison Control Center immediately. Do not wait for symptoms to appear — early intervention is critical to a successful outcome. https://www.aspca.org/pet-care/animal-poison-control
How much xylitol is toxic to a dog? Xylitol toxicity in dogs is dose-dependent, and dangerous effects can occur at very low amounts — in some cases, less than a single stick of sugar-free gum is enough to cause hypoglycemia in a small dog. Because safe thresholds vary by a dog's body weight and the concentration of xylitol in the product, any suspected ingestion should be treated as an emergency. Contact your veterinarian or a poison control hotline right away. https://www.aspca.org/pet-care/animal-poison-control
What are the signs of xylitol poisoning in dogs? Clinical signs can appear within 15–30 minutes of ingestion and may include vomiting, lethargy, weakness, loss of coordination or stumbling, muscle twitching, disoriented behavior and, in severe cases, seizures. Depending on the amount consumed, life-threatening liver damage is also possible. If you observe any of these signs — or even suspect exposure — seek veterinary care immediately rather than waiting to see if symptoms worsen. https://www.aspca.org/pet-care/animal-poison-control
Is xylitol toxic to cats? Research on xylitol toxicity in cats is limited. Cats may be less frequently exposed because they tend to be more selective about what they eat, and their metabolism differs from dogs. However, because the potential for harm exists and confirmed safe exposure levels have not been established, the conservative recommendation is to keep all xylitol-containing products out of reach of cats as well. When in doubt, consult your veterinarian. https://www.aspca.org/pet-care/animal-poison-control
Is peanut butter safe to give my dog? Plain peanut butter without xylitol is commonly used as a treat or to help administer medication, and many dogs enjoy it. The critical step is reading the ingredient label every single time — some brands, particularly reduced-sugar or "natural" varieties, have added xylitol as a sweetener. Never assume a product is xylitol-free based on brand familiarity alone, as formulations can change. https://www.aspca.org/pet-care/animal-poison-control
Can I use human toothpaste to brush my dog's or cat's teeth? No. Human toothpastes frequently contain xylitol and should never be used on dogs or cats. Always choose a toothpaste formulated specifically for dogs or cats, which will be free of xylitol and safe if swallowed. Your veterinarian or a knowledgeable Petco associate can help you find the right dental care products for your pet. https://www.aspca.org/pet-care/animal-poison-control
What should I do if I think my pet ate something containing xylitol? Act immediately — do not wait for symptoms to appear. Contact your veterinarian or the ASPCA Animal Poison Control Center (888-426-4435). Be ready to share your pet's weight, what was ingested, approximately how much and when. Early treatment dramatically improves outcomes, so speed matters more than anything else in a potential xylitol exposure. https://www.aspca.org/pet-care/animal-poison-control
How much xylitol is toxic to dogs? Xylitol toxicity is dose-dependent, and the threshold is alarmingly low. Even a very small amount — in some cases less than one stick of sugar-free gum — can trigger dangerous hypoglycemia in dogs. Higher doses are associated with life-threatening liver failure. Because safe thresholds vary by a dog's body weight and the xylitol concentration in the specific product, there is no universally "safe" amount. If your dog has consumed any product containing xylitol, contact your veterinarian or a poison control helpline immediately rather than waiting for symptoms to appear. https://www.aspca.org/pet-care/animal-poison-control
What should I do if my dog ate something containing xylitol? Act immediately — do not wait for clinical signs such as vomiting, weakness or seizures to develop. Call your veterinarian or the ASPCA Animal Poison Control Center right away and have the product packaging on hand so you can report the ingredient list and the amount consumed. Time is critical: the faster treatment begins, the better the outcome. Do not attempt to induce vomiting or administer any home remedy without direct guidance from a veterinary professional. https://www.aspca.org/pet-care/animal-poison-control
Are all sugar-free products dangerous to dogs? Not every sugar-free product contains xylitol — some use other sweeteners such as stevia, sorbitol or sucralose — but you cannot assume a product is safe simply because it is labeled "sugar-free." Xylitol may appear on an ingredient label under names including "birch sugar" or "wood sugar," and it is present in a surprisingly wide range of products, from chewing gum and baked goods to personal care items and some medications. Always read the full ingredient list before allowing your dog anywhere near a sugar-free item, and when in doubt, keep the product out of reach entirely. https://www.aspca.org/pet-care/animal-poison-control
Is xylitol toxic to cats as well as dogs? Research on xylitol toxicity in cats is limited compared to what exists for dogs, and confirmed clinical cases are rare. This may reflect cats' famously selective eating habits or differences in feline metabolism. However, because the potential for harm cannot be ruled out, the conservative and recommended approach is to keep all xylitol-containing products away from cats just as you would from dogs. When in doubt, consult your veterinarian. https://www.aspca.org/pet-care/animal-poison-control
Which everyday products most commonly contain xylitol? Xylitol turns up in a wider range of household products than most pet parents expect. The categories most frequently associated with accidental pet exposure include sugar-free chewing gum and mints, certain peanut butters and nut spreads, baked goods made with xylitol as a sugar substitute, human toothpastes and mouthwashes, some over-the-counter liquid medications and chewable supplements, and select personal care products such as lip balms and baby wipes. Checking ingredient labels on all of these product types — especially before using peanut butter as a treat or pill pocket — is a straightforward habit that can protect your dog's life. https://www.aspca.org/pet-care/animal-poison-control
Should I use human toothpaste or mouthwash on my dog? No. Human oral care products — including toothpastes, mouthwashes, breath sprays and whitening strips — frequently contain xylitol and should never be used on dogs or cats. Always choose toothpastes and oral rinses specifically formulated for pets, which are free of xylitol and other ingredients harmful to animals. Your veterinarian or a knowledgeable Petco associate can help you select an appropriate product for your pet's dental care routine. https://www.aspca.org/pet-care/animal-poison-control
This article was created with assistance from AI tools and reviewed for accuracy by Petco's content team.
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