My chameleon is lying at the bottom with splayed legs. Is it MBD?

This sounds like metabolic bone disease. Very common symptom for this is loss of use of the back legs due to calcium deficiency. I doubt it has anything to do with him climbing around on you other than that activity used up the available calcium he had in his body. Are you sure your husbandry is 100% correct? Diet, lighting, temperature, supplements, etc. This is almost always due to improper husbandry. I suggest you review all of your husbandry and get him to a reptile vet for treatment. ( https://mypetchameleon.com/diseases/metabolic-bone-disease/ ) ( https://www.pahvets.com/exotic-animal-vet-albuquerque/ )

Sounds like MBD. Without more information all I can tell you is that you should take them to see a reptile veterinarian. This could be trauma/injury but honestly, most problems we see with reptiles are due to improper diet and/or husbandry. I would to know how long you have had them, what is their cage setup, what is the lighting/temperature/humidity set up, what diet have you been feeding, any supplements? How long were you gone? Etc. I don't have enough information to go on. ( https://www.lbah.com/reptile/chameleon-bone-disease/ ) Here is a list of reptile vets in PA. You will need to see if any are near you. You may have to drive a ways to find one..... ( https://www.thesprucepets.com/exotic-pet-veterinarians-in-pennsylvania-1239016 ) Hope this helps. If you have more questions you can always opt for a private consultation where we can chat back and forth. That way you can ask as many questions as you'd like. Best wishes.

Thanks for reaching out about the chameleon and including pictures. The first photo with the swayed back is very suspect of MBD/calcium deficiency. Diet and husbandry need to be review and correct, and a veterinary visit should be scheduled ASAP. Typically concerns are poor calcium in the diet, lac of UV light, poor temperature, etc. This is an emergency. Good luck.

Thanks for reaching out about Charlie. Concerns would be a spinal or back injury, possibly while struggling. A veterinary visit is recommended to assess and provide a diagnostic treatment plan. Back injuries are more likely to respond to treatments earlier than later. Remove perches and provide a comfortable surface on which to lie, such as clean towels. Good luck.

Give him a day or two to fully recover. Monitor for swelling or bruising. If he doesn't regain full strength, have hm examined by your veterinarian or an experienced herp veterinarian. Increase enclosure temperature to aid in healing and keep him as stress free as possible.

Check the temperature of the enclosure. Low temps can affect appetite and activity in reptiles. Soak her in a warm 50/50 solution of water and unflavored PediaLyte for 20-30 minutes daily to treat or prevent minor dehydration. Make sure prey is appropriately sized, no bigger than the space between her eyes. If the behavior persists, have her physically examined by your veterinarian or a vet experienced in treating reptiles to diagnose and treat illness or injury. Review the information at the link below for care of veiled chameleons. http://www.reptilesmagazine.com/Care-Sheets/Lizards/Veiled-Chameleon/

This is probably due to improper UV lamp and possibly not enough Calcium in the diet causing MBD. you need to get a new UVB bulb and you need to change it every 6 months, you also need to sprinkle calcium powder on his food every day.