Thanks for reaching out about Minn and including photos, although the lesion can not be identified through the pictures. Is the eye protruding more than the other? Popeye can be caused by multiple problems including an infection, mass behind the eye, increased intra-ocular pressure and more. Many of these are difficult to treat but none of the over-the-counter remedies work. Test and correct water quality for pH, ammonia, nitrites and nitrates. Review diet as pellets/flakes should be purchased every 3 months as vitamins (especially vitamin C) degrade quickly. If continues to progress, a veterinary visit with an experiences aquatic veterinarian is recommended. Good luck.