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My betta has popeye, and my treatments aren't working. What's next?

Updated on September 23rd, 2025

Pet's info: Fish | Betta | Male | unneutered

Trying to treat betta for Popeye otherwise healthy happy and active. Moved from five to three gallon filtered heated tanks. Feed freeze dried blood worms, daphnia and bug bites by fluval. Also am changing some if not all water every few days. Treated with kanaplex several doses no real improvement. Switzed to metroplex in water treatment as I don't know how food treatment works or how to dose started four doses two days apart and there is some improvement to the eyes. Med is miconidazole.

1 Answer

Most Helpful Answer

Todd Cecil

Answered By Todd Cecil

Veterinarian

Published on March 6th, 2020

Thanks for reaching out about Betta. Rarely do the water additives do anything, as fresh water fish do not drink as water passively crosses through gills, into the body due to saline nature of the body. The antibiotic molecules are too large to pass. So water additives might be good for skin lesions (acting as a topical). Not much is known regarding orally administered meds also and how they are intestinally absorbed. Giving antibiotics through injections is the preferred method for success, but a veterinary visit is needed to prescribe. The cause of the pop-eye is the challenge, which could be corneal scratches with secondary infections, bacterial abscess behind the eye, gas bubble disease and more. A veterinary visit is recommended.
Good luck.
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