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My senior Yorkie is unwell after vaccines. What signs should I watch?

Updated on September 23rd, 2025

Pet's info: Dog | Yorkshire Terrier | Male | neutered | 12 lbs

My 11 year old Yorkshire Terrier had three vaccinations today from a veterinarian in NYC today. Rabies / DA2PP / Leptospirosis. He does not seem well and has not been himself at all when we got home. Could this bundle be toxic for him and what are the signs I should be looking for? He has also been.diagnosed with a heart murmur and has been taking Vetmedin 5mg half tablet every 12 hours for the past 5 to 6 months. Thank you so.much! I am waiting for a response with immense gratitude

1 Answer

Most Helpful Answer

Dr. Melanie, BVSc MS

Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on June 2nd, 2017

Hello there! I'm sorry Max isn't himself tonight. It is normal that a dog can be lethargic after receiving their vaccines, and you could even see a decrease in appetite. I would be concerned if he was experiencing persistent vomiting and diarrhea, itchy skin or hives, swelling around the muzzle, face, or eyes, severe coughing, difficulty breathing, or collapse. Should you see any off those signs, I would rush him into a vet immediately. The side effects of the vaccines should pass within 24-48 hours, but if he still isn't himself after that time, it would be a good idea to have him seen by a vet. Given that he has a heart murmur, that could also be a cause of him not acting normally, and that should be evaluated by a vet. Good luck, I hope this helps!
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