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My puppy threw up yellow after first vaccines, is this normal?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Male | unneutered | 2 months and 16 days old | 3.8 lbs

My puppy had his first set of vaccines this morning and just threw up yellow mucus, should I bring him in?

1 Answer

Most Helpful Answer

Lauren Celestin, DVM

Answered By Lauren Celestin, DVM

Veterinarian, Veterinary Dentistry Resident

Published on July 5th, 2017

Hello! Sounds like Gus vomitted up some bile. As long as this was the only instance of vomit and he otherwise appears to be acting like himself, I would not worry. It's unlikely that the vomit is related to the vaccines as vaccine reactions typically happen immediately or within a couple of hours after administration of the vaccine. Continue to keep an eye on him for any other episodes of vomiting or changes in his behavior. Hopefully this was a one time event and won't cause Gus or you to miss a beat! Hope this helps.
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