Puppy dribbles pee, has accidents, UTI meds not working. What to do?
If the antibiotics didn't make much difference, I'd be suspicious of puppy vaginitis, which is a relatively common inflammatory condition that can lead to accidents and sometimes make them more susceptible to urinary infections. It generally resolves with age. I would also check for a stricture (this may require sedation as they don't love vaginal palpation...).
For now, since your vet hasn't been able to check a urinalysis, that would be the first priority. See if you can get a sample- sneak a small container under her when she squats. If you have to hold onto the sample a few hours before dropping it at your vet, stick it in the fridge, but the fresher the better. If you're having no luck, your vet can collect a sterile sample via cystocentesis. Hope this helps.
Updated on September 23rd, 2025