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How long should I wait to give my dog Trifexis after flea shampoo?

Updated on September 23rd, 2025

Pet's info: Dog | Black Mouth Cur | Female | spayed | 1 year and 3 months old | 50 lbs

CARESHARE I just treated my dog for fleas with advantage shampoo. How soon can I give her the Trifexxus preventative? She was due for it when I found a flea on her but wasn't sure if I should give her both at the same time.

1 Answer

Most Helpful Answer

Published on January 23rd, 2019

I would suggest to ideally wait 7 days before giving any other treatment to be on the safe side.
The two might be given together as they have different active molecules but I would recommend always to give them at different times (one week apart).

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