Can I give my dog more Trazodone/Gabapentin before dental cleaning?

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Duke. I'm sorry that he's been struggling lately, how hard for him and you. You can use the gabapentin and trazadone together. Yes, they can cause increased sedation together, but that may be a good thing if he's sundowning. It will help him sleep and keep him on a regular schedule. I hope this helps!

Yes you can give it with the other medications. Personally I’d not give Nico the gabapentin when giving the trazodone just to be extra cautious since you’ll only be giving it one night for the fireworks. Thanks for using Petco Pet Education Center, formerly Petcoach to help you get answers to your veterinary questions.

I am a veterinarian, and yes it is safe to combine gabapentin and trazadone. Without seeing your puppy in person, I cannot say specifically it is safe for your dog, but it is a combination that can be used. I hope this helps!

Thanks for using Petco Pet Education Center, formerly Petcoach! Sometimes it can take a bit longer for these medications to kick in. It is generally not recommended to use these medications more frequently than how they are recommended as that can result in undesirable side effects such as gastrointestinal side effects with carprofen and significant sedation with gabapentin. For that reason, it would best to wait till the morning if that is what was recommended by the prescribing veterinarian. If you are asking if these two medications can be given together 4 hours apart then the answer would be yes. Good luck!

I cannot find any interaction reports for Trazodone with carprofen (Rimadyl), however there are reports that Trazodone has interactions with Ibuprofen, a similar class of NSAID. This reports that either increases toxicity of the other by added drug effects. Check with your veterinarian on whether he recommends giving the two together. There maybe less toxic effect by giving the Rimadyl in the morning and the Trazodone in the evening. However this is for your vet to decide. If you cannot reach your veterinarian I suggest not to give the Trazodone tonight and keep the dog in a room where she is not likely to be bothered much by trick or treaters.

Generally, we don't expect that these four-a-day medications are given exactly at six hours and it's understandable/okay to have a longer (two extra hours or so) period between pills overnight. This would mean the day ones are given closer together, which is fine for this medication. I hope that helps and Jasmine gets better soon.

Trazadone can be given once or twice daily to dogs. Side effects include increase/decrease in appetite, GI upset (vomiting, diarrhea), sedation, agitation, ataxia (wobbly gait). His past history of pancreatitis is likely not an issue with this medication. If he takes any other medications, consult first with your vet before giving them.