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Is it safe to give Sentinel for heartworm after Advantix for fleas?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Male | neutered | 3 years and 8 months old | 14 lbs

Hello I’ve been giving my dogs Sentinel for heart worm, flea, and tick treatment every month. I recently found fleas on my dog, and purchased Advantage/Advantix to treat my cats/dogs. Can I continue to use Sentinel mid-month for heart worm treatment after giving him Advantix for fleas, or would this be an overdose of some kind?

1 Answer

Most Helpful Answer

Answered By Vanessa Yeager DVM MPH

Veterinarian

Published on October 3rd, 2017

Hi and thanks for your post!

Yes this is okay.

Sentinel does not kill adult fleas, just the eggs. Sentinel also does not prevent ticks as you mentioned in your question. Advantix does, however.

I hope this helps!

1Pet Parents found this answer helpful

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