My dog has a recurring blister on his paw and lip. What to do?

I would recommend that you have Mo examined by a vet. From the pictures, these don't look like blisters. They could be caused by allergies, foreign bodies, autoimmune disease, deep bacterial or fungal infection, etc. The vet may need to do a biopsy to see what the cause is so that Mo can receive appropriate treatment.

Even though a picture would help to understand better the underlying cause, this presentation could be due to a trauma (presence of foreign bodies) or localized spot of skin infection (likely to be caused by bacteria). Allergic reactions can cause them as well in rare cases. A check up, appropriate disinfection and possibly antibiotics (oral, topical or in a shampoo formulation) are needed to solve the problem. If the problem is related to the presence of foreign bodies then a quick surgical procedure (sometimes even under local anesthetic) is needed to remove them. Disinfection can eventually be started at home with very diluted hibiscrub or betadine or salted water baths. Buster collar may be useful as well to avoid any licking. Please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

Ouch! That should likely be checked out by your vet in person. Tumors on the toes can aggressively appear and spread like this, and other issues such as burns, blisters, cysts, sores, infections, etc should be treated by your vet. They can take a sample of the affected tissue to look for the cause behind it, and provide treatment options such as removal, antibiotics, medicate shampoos, and more. Until you can get to your vet, it's best to keep the area clean and dry and to keep Bossy from licking at it with an Elizabethan (cone) collar. This can help reduce irritation.

Poor Gizmo! That looks really sore. The lesion in the picture could be an abscess, a very large interdigital cyst or a tumor. I would recommend that you have Gizmo seen by your veterinarian. They may recommend a fine needle aspirate of the lesion to get a better idea of what is causing the swelling. Surgery may be required to lance and drain the abscess or remove a mass if present.

Poor Zues - those lesions are quite prominent! Recurrent interdigital (between the toes) lesions can be frustrating and can be caused by a number of different issues, including atopy (environmental allergies), food allergies, bacterial infections, yeast infections, mange, autoimmune issues, or even cancer. In many cases, secondary bacterial infections occur when dogs lick or chew at their feet, meaning that the bacterial infection happens on top of another cause, like allergies. This might explain why the antibiotics helped initially, but the lesions then recurred. At this point, it sounds as though more diagnostic testing is needed. Your vet will likely want to do some skin cytology (examining some cells under the microscope) to check for signs of bacteria and/or yeast, a skin scrape to check for the mites that cause mange, and may even recommend taking a biopsy so that a pathologist can evaluate the affected tissues. Depending what those tests show, your vet may then recommend trying allergy medications (such as Apoquel or Cytopoint), a prescription hypoallergenic food trial, or other medications. I understand how frustrating this issue must be and wish you and Zues all the best!

From your picture it appears that Stamford may have an interdigital cyst. These can occur due to foreign material such as grass seeds as well as allergies or infections. Interdigital cysts can be painful and difficult to resolve - sometimes taking many rounds of antibiotics or even surgery. Epsom salt soaks can be helpful in conjunction with antibiotics and the pet should not be allowed to lick at the area. Other potential causes for the lump would be an abscess or a growth. If the lesion is not improving or becomes worse I would recommend that you have Stamford examined by your veterinarian

Lesions like this can be related to acne, folliculitis or allergies. Typically this does respond to antibiotics but if allergies are the issue, the condition can reoccur. Dogs breeds with heavy jowls/lips are more prone to this condition. Washing all the food/water dishes and all chew toys once a week can help. Your veterinarian may also carry medicated wipes the clean the area daily. Lastly, if allergies are suspected, Jax may need a special diet or even blood testing to determine the offending allergen. I hope this helps and please feel free to post any additional questions.