Is it safe for my dog to take metoclopramide and prednisone together?

If I'm understanding her medication plan correctly, I'm a bit concerned because Metacam and prednisolone should not be given together - this combination of drugs can cause serious side effects such as stomach ulcers and internal bleeding, and I do not know of any veterinarians who would recommend giving both at the same time. I would recommend calling your vet in the morning to clarify the medication instructions, because it could be very dangerous for Peapumpkin to take both of these medications at once.

It’s safe to use the prednisone with the dexamethasone shot, they are in the same class of steroids. I would wait more like 5-7 days between the last prednisone and the Rimadyl. Longer if Toby is prone to stomach upset or diarrhea. When used closely together, these two classes of medications can cause bleeding stomach ulcers.

Hi, There are no interactions between the two drugs and they are often given together as the omeprazole helps to protect the stomach from potential side effect that can damage the stomach and cause ulcer by steroids. The instruction to take them differ a bit, the omeprazole is to be taken on empty stomach preferably in the morning before the first meal and steroids are to be taken with food or after a meal (full stomach). Hope this helps

The problem I see with these medications is that he is taking a steroid (prednisone) and an a non-steroidal (NSAID) - meloxicam at the same time. It is not recommended those be given together. I suggest you talk to your vet about this issue. ( https://criticalcaredvm.com/a-potentially-lethal-combination/ ) I would be worried about this as this can negatively impact the stomach, kidneys and liver. Your vet needs to decide which one he should be on (the NSAID or the steroid) and stop the other one. Divi should also be given some gastroprotectants to prevent stomach ulceration.

Great question! No, you absolutely CANNOT give a steroid (prednisone) at the same time as a NSAID (Metacam). This is a very big no-no! This can cause huge, life-threatening side effects. He can take a muscle relaxant and/or an opiate along with the steroid. You should also you vet about these medications as they are prescription medications. All these medications work synergistically together. You should also consider acupuncture. It works wonders for these injuries. Hope this helps. Best wishes.

Prednisone can absolutely cause behavior changes and mood alterations. The side effects are usually at their greatest during the first two to four week of therapy as the body grows accustomed to glucocorticoid drugs. The metronidazole is not likely a cause of any side effects you are currently seeing. If you are consulting with a oncologist regarding Pepe's case, do not hesitate to contact them with any questions involving his therapy. These cases can often be complex and require a lot of special attention to drug interactions. Anyway, if you require further consultation please let me know. Hope this makes sense.

Hi there. In general, there is no reason that prednisone can't be given with Cosequin DS. As long as the prednisone was prescribed by your veterinarian and you're giving it according to his/her instructions, this should be fine. :)