Petco Text Logo
Petco Pet Logo
  • Two Easy Ways to Start Earning Rewards!

    rewards header
    Become a member today!
    Members-only pricing and offers, personalized care notifications, Vital Care points back on every purchase and more!
    Petco Pay LogoBecome a credit card member today!

    Earn 2X Pals Rewards points at Petco
    when you use Petco Pay!

    APPLY NOW
    Learn More About Petco Pay Benefits

Is it safe to give my dog prednisone and dexamethasone together?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Male | neutered | 11 years and 11 months old | 19 lbs

My dog was given a shot of dexamethosone for sever arthritis and 5 days of prednisone. I am questioning if you can give prednisone in addition to Dexamethosone. I was told also to withhold Rimadyl until a day after stoppingprednisone for a washout period. From what I have been reading, there should be a longer washout period before starting back the Rimadyl. What is your opinion?

1 Answer

Most Helpful Answer

Jenna Beyer, DVM, MBA, cVMA

Answered By Jenna Beyer, DVM, MBA, cVMA

Veterinarian, Certified Veterinary Acupuncturist

Published on June 7th, 2020

It’s safe to use the prednisone with the dexamethasone shot, they are in the same class of steroids. I would wait more like 5-7 days between the last prednisone and the Rimadyl. Longer if Toby is prone to stomach upset or diarrhea. When used closely together, these two classes of medications can cause bleeding stomach ulcers.
Vote Icon1Pet Parents found this answer helpful

Smart Picks for Smart Questions

Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Share

Styled arrow button