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My dog is on Meloxicam & Prednisone. Is this safe for his liver?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed | Male | unneutered | 9 months and 6 days old | 19.07 lbs

Hi! My dog is currently taking Metronidazole 500mg, Meloxicam 7.5mg and Prednisone 5mg. I guess he's taking too much medicine prescribed by a vet for his inflamed and swelling foot due to his tight bandage and bacteria in his poop and I guess he's still young for taking such medicines. What can I do for his diet to prevent any liver disease or stabilize his liver function?

1 Answer

Most Helpful Answer

Dr. Strydom, DVM

Answered By Dr. Strydom, DVM

Veterinarian

Published on April 8th, 2019

The problem I see with these medications is that he is taking a steroid (prednisone) and an a non-steroidal (NSAID) - meloxicam at the same time. It is not recommended those be given together. I suggest you talk to your vet about this issue.

( https://criticalcaredvm.com/a-potentially-lethal-combination/ )

I would be worried about this as this can negatively impact the stomach, kidneys and liver. Your vet needs to decide which one he should be on (the NSAID or the steroid) and stop the other one. Divi should also be given some gastroprotectants to prevent stomach ulceration.
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