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My dog has high creatinine and heart issues. Is meropenem the cause?

Updated on September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Male | 1 year and 10 months old | 66.1 lbs

My pet was previously treated with clindamycin, metronidazole and Doxycycline and it showed good results and after the end of therapy again problems started and meropenem injection was given by doctor, now it is showing high creatinine level of 10 and round heart in x-ray. Is it due to the effect of meropenem?can it be treated and cured? Please help me.

1 Answer

Most Helpful Answer

Dr. Strydom, DVM

Answered By Dr. Strydom, DVM

Veterinarian

Published on November 24th, 2019

It is difficult to say if the elevated creatinine is due to the medications or not since you don't have a "before" creatinine. Meropenem is not known to cause renal side effects unless the dog already had a renal condition to start with. The known side effects of meropenem may include: nausea, vomiting, diarrhea, skin rashes, phlebitis, eosinophilia, transient elevation of liver function tests and seizures (esp. in patients with CNS dysfunction and renal failure). I don't have enough information to know if he can be cured. You didn't say what his original problem was. Why was he given all those antibiotics? What was the illness?
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