My dog has Mdr1*. Is it a mutant gene or different from Mdr1?

Hello. It is important to know with Border Collies, and other Collie mixes in particular, whether they are MDR1 normal or not to ensure you use the proper products on Tasha. You can just assume she has an abnormal gene and get products that are safe for an abnormal gene. However, if the clinic is still practicing where you took Tasha before, you should be able to get her records, as records should be kept for 5 years and Tasha is only 4 years old, so you can try to call the vet and get these records. You can also try discussing with your vet about which lab the test would have been sent to, as the lab that ran the test may have a record of it as well. You can, of course, get her tested again as well. These are all options. Good luck with Tasha.

Hello and thank you for posting your question on Petco Pet Education Center, formerly Petcoach! Genetics for hair or coat color and the gene for MDRI are not known to be linked. The mutation is commonly seen in herding breed dogs and can be tested for through a blood sample or cheek swab that is available through most veterinary clinics. This is the only definitive way to know if your dog has the gene mutation. I hope this has helped and best wishes to you!

MDR1 can be tested very easily by most veterinary laboratories, you will need to take Morty to the vet, they will take a blood sample then they will send it to the lab, within 3-4 days you should get an answer.

Hello and thank you for your post again on Petco Pet Education Center, formerly Petcoach! The MDR1 mutation is not commonly found in Beagles. Herding breeds or breeds her herding descent are the most effected. All other breeds, have a less than 5% chance of carrying the mutation. I hope this has helped! Best wishes to you.

This supplement has no concern with a dog that has a MDR1 gene mutation. There are no safety concerns with glucosamine, or the other ingredients in this product, so no worries about giving it with her condition. For more information about this condition I recommend you read the article at the following link: https://vcahospitals.com/know-your-pet/multidrug-resistance-mutation-mdr1 I hope that helps and all is well with Lovey.

None of these medications should cause problems related to Tasha's MDR1 gene. Personally, I prefer giving oral deworming medications rather than injections, but as I said, this is purely personal preference. Either Droncit or Dolpac 10 should be effective to treat tapeworms and it should not be an issue to administer the additional active ingredients in Dolpac 10. Many deworming medications contain more than one active ingredient and simply provide for a more broad spectrum of treatment. If Tasha would experience a reaction to the Dolpac 10 (which would be quite unusual), you could also ask your vet if he can prescribe Droncit tablets from either a local or online pharmacy if you are more comfortable with this course of treatment.

Technically, all heartworm preventatives (even those with ivermectin) are safe in dogs with an MDR1 gene mutation since the effective dose of medication in heartworm is significantly lower than that which would cause neurotoxicity. However, most vets will preferentially choose selamectin (Revolution) or milbemycin (Interceptor) based products for MDR1 mutant dogs over ivermectin (Heartgard) based products. If Tasha has historically been very sensitive to heartworm preventatives, I would advise giving her flea/tick prevention and heartworm prevention 2 weeks apart rather than simultaneously. Your vet will be able to perform a blood test for heartworm disease prior to starting Tasha on a heartworm preventative, as all are prescription based.