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My dog's green nose discharge returns after antibiotics. What's wrong?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 3 years and 11 months old | 57 lbs

Hello. My dog has had a mucous discharge from her nose for over a year. 4-5/day, slightly green, goes away with antibiotics but comes back shortly after. Xrays of skull, nasal passageway, chest show nothing. Blood test showed elevated white blood cells and liver enzymes. Mood, appetite, weight, energy all normal. Any ideas what this may be?

2 Answers

Most Helpful Answer

Joy Fuhrman, DVM, MBA, CPA

Answered By Joy Fuhrman, DVM, MBA, CPA

Veterinarian

Published on December 29th, 2017

This could be a fungal infection or an antibiotic resistant bacterial infection. If bacterial and fungal cultures have not yet been performed, I would recommend that you request them. I would also suggest a consultation with a veterinary internist for a rhinoscopy with possible biopsies. You can find one in your area on www.acvim.org.
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Related Answers from Veterinarians

  • Answered By Lindsey Edwards MVB, BSc, IVCA

    Veterinarian

    Published on June 1st, 2017

    Poor Hubcap, at this stage at may be neccessary to perform further tests such as culture of the discharge, endoscopy or MRI to identify exactly where the infection is coming from and why it is not resolving completely with medication. Foreign bodies such as grass seeds and tumors or cysts can all cause ongoing infection/discharge which recurs despite appropriate antibiotic treatment. Schedule a recheck and consider referral to a specialist if required

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    1Pet Parents found this answer helpful

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