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My cat has pyometra. Should I spay her or try hormonal therapy?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Female | unspayed | 8.5 lbs

My cat is a female domestic shorthair, roughly 4/5 years old. She has all her shots. No kitty leukemia. She has a high white blood cell count. She has been eating, drinking, peeing and pooping regularly. Three days ago she had a discharged from her vagina. It was light cream color with a tinge of dark brown (like old blood) The vet I took her to saus she jas pyrometra. What are the chances of a succesful "spay" vs hormonal therapy. also how successful is the hormonal therapy &what are the risks?

1 Answer

Most Helpful Answer

Dr. Melanie, BVSc MS

Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on April 27th, 2017

I'm sorry Quai has a pyometra! In terms of a spay vs hormones, spaying her is the best option. While it is a more difficult surgery, cats who are diagnosed in the early stages of the disease are very good surgical candidates. The success rate for medical treatment with hormones is widely variable and not without considerable risk and potential long-term complications. These hormones are not always successful at treating the pyometra, and there are side effects to the hormones including restlessness, panting, vomiting, salivation, and abdominal pain. In addition, because prostaglandins (the hormone used) causes uterine contractions, the uterus itself has the potential to rupture and spill infection into the abdomen causing peritonitis. For the best possible outcome, I would recommend spaying Quai.
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