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My adult cat needs first vaccines. Is it safe? All at once or spread?

Updated on September 23rd, 2025

Pet's info: Cat | American Shorthair | Male | unneutered | 3 years and 4 months old | 6.8 lbs

Hi there. My cat, who is 3.7 years old and is a healthy male, has never been vaccinated due to certain personal circumstances. This year I am moving to Europe, and as a result I will need to get my cat vaccinated several times as well as microchipped. I'm very scared that he might have an adverse reaction since he has never been vaccinated before. Please let me know if vaccinating him is safe at this point, and should he get his shots all at once or one shot at a time? Thank you in advance.

1 Answer

Most Helpful Answer

Destini R. Holloway, DVM

Answered By Destini R. Holloway, DVM

Veterinarian

Published on February 22nd, 2020

I can understand your concern. Vaccine reactions in pets can’t be predicted and is pretty uncommon, with less than 5% of pets having them and even less so in cats. It is necessary in this situation to get Kiski vaccinated so it is best to start the process with your vet. You could also request that he get a pre-vaccination shot to help reduce his chances of a reaction even further. Ask your vet about this when you schedule your appointment or get his immunizations started. And lastly the latest studies suggest that getting all the vaccine done at once instead of spreading them out, reduces the chances of a reaction occurring because you are not challenging the body’s immune system multiple times versus once or twice, if boosters are needed.

I hope that things go well for your pet Kiski moving forward. Take care. : )
Vote Icon1Pet Parents found this answer helpful

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