My guinea pig has crusty eyes for years, now bald spots. What's wrong?

In my experience the huge majority of skin issues in guinea pigs falls into two categories: mites and fungal. It's uncommon to see flaking skin and hair loss without it being one of these disorders. Ringworm would be a concern and is very common in guinea pigs. Instead of being a worm, it's actually a skin fungus, and doesn't always have the classic "ring" shape. The only way to diagnose ringworm in guinea pigs is doing a fungal culture where you collect hairs and put them on a culture medium. It can take 10-14 days to get a result, though most positives show up within the first week. If you don't want to do the testing then what you can do is treat those scabs with an over the counter anti fungal cream like clotrimazole. It is basically jock itch cream. Apply a thin layer 2 times a day. It won't hurt anything if it is not ringworm but if it is ringworm, it will help. If you are going to shampoo him I would use a medicated shampoo like this one: https://www.1800petmeds.com/Malaseb+Shampoo-prod10667.html Lather it on, let it sit for 5-10 minutes and then rinse. The contact time of the shampoo is very important! This shampoo has an antifungal agent in it as well as an antimicrobial agent. If you try the ringworm cream and shampoo and it doesn't help at all within 7-10 days then I would recommend you get a second opinion from another vet and find a vet that specializes in treating exotic pets as he may have skin mites. Skin mites in these pets will always cause itching, sometimes severe enough to lead to seizures. If he is itchy then skin mites are very likely. Skin mites need to be treated with Ivermectin injections spaced 10-14 days apart and need to be done by a vet. Usually 2-3 injections are needed to clear the mites. If your vet doesn't specialize in treating exotic mammals/pocket pets then I would suggest you find one that does. I found this vet in your area based on your zip code: http://www.acsevh.com/ I hope this helps. Best wishes!

Poor Betty this looks sore! I would say this is due to an infection of some sort. It could be bacterial even coming up from the resp tract but the flouroquinilone should have helped. Otherwise it may be a parasite or fungus such as ringworm. I would get a skin scrape checked and have a hair brushing sent off for ringworm. I know you have tried antifungal cream, sometimes canestan works but at times they need stringer treatment from the vet. You could also try an antiparasite treatment such as xeno.

Thanks for reaching out about Periwinkle and including photos. Try cleaning the eye area with a soft moistened cloth. If appears white/creamy or persists, a veterinary visit is recommended to assess and provide a diagnostic/treatment plan. Continue to monitor appetite. Good luck.

My best guess is that this could be ringworm however it is impossible to tell just by looking at a photo. I suggest you get this spray and apply it 2-3 times daily on the affected area. ( https://www.petco.com/shop/en/petcostore/product/vetericyn-plus-antimicrobial-wound-and-skin-hydrogel-for-pets ) If after a week to 10 days it still is not resolving then you need to take her to a vet for an exam. Wash your hands thoroughly after touching her as ringworm, if it is that, is contagious to people.

Sorry to see this has happened to poor Ellie. She requires immediate veterinary attention as this eye is badly infected and will be very painful. I suspect she has developed a bad corneal ulcer or there has been trauma to the eye. She needs to assessed by a veterinarian and appropriate treatment given. They may be unable to save the eye.

Mochi's eye does look like there is infection. Have her examined by your veterinarian for confirmation. She will likely need antibiotics if infection is diagnosed. Use a warm washcloth to gently clean the eye, change bedding frequently to minimize irritating dust. If you are using pine or cedar shavings, immediately clean the cage and use aspen shavings or recycled paper bedding. The cedar can be irritating and may cause liver disease.

Thanks for reaching out about Sunny. Try wiping with a moistened warm wash cloth to keep clean. Do not use soap or any topical medications, not prescribed by a veterinarian. Contact the pet store to see if they can assist. If the eye gets worse, a veterinary visit is recommended.