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My senior Lab's arthritis isn't responding to Rimadyl. What next?

Updated on September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Male | neutered | 10 years and 5 months old | 100 lbs

I have a 10 yr old 100 lb yellow Labrador retriever. He has significant arthritis in his rear knees and is having a difficult time getting up from laying down, going up/down stairs from porch, slow to sit. He has been seeing a veterinarian regularly and has been in rimadyl once a day for 6 months and 2x/day for last 3 months. It does not seem to be helping. I cannot seem to get a straight answer for what to try next. Given my dogs situation I just want name of one medication to try next.

1 Answer

Most Helpful Answer

Dr. Strydom, DVM

Answered By Dr. Strydom, DVM

Veterinarian

Published on March 6th, 2020

You should ask your vet about combination therapy. I would use the Rimadyl in conjunction with Tramadol or Gabapentin. In combination the medications work together synergystically and enhance each other. If those don't help the next thing I would try is either Meloxican or Piroxicam in place of the Rimadyl.
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