My puppy threw up after Trifexis. Is this a common side effect?

Poor Ember! Vomiting and lethargy are both common side effects of Trifexis, and do not usually indicate any kind of serious problem. But, you could certainly opt to use a different flea and heartworm medication for her in the future to avoid this issue. For tonight, I would withhold food and leave her alone to rest since she doesn't feel well. If she's still acting noticeably lethargic tomorrow, or if she develops any other symptoms, then I would call your veterinarian or take her in for a check-up to make sure nothing else is wrong.

The age and pound limit for puppies is 8 weeks and 5 lbs. It would appear that Luna is within this range. The most common listed side effects for Trifexis include itchiness, anorexia, lethargy, redness and diarrhea. Often drugs may have other side effects that are considered uncommon and/or rare. There is also the possibility of allergic reactions to medications. If Luna appears to be in true distress to you, I would recommend getting her into a vet particularly if these side effects happened immediately after using the drug. Intervention may be required, and time is of the essence in smaller, younger patients. Hope this helps.

Six hours is sufficient time for Stella to digest the Trifexis. If you didn't see the pill in the vomitus, then she digested it. Typically, another dose is recommended only if vomiting occurs within 1 hour of administration.

Toxic reactions of the main ingredient in Trifexis in dogs starts at 400mg/kg. Assuming duke had 6 tablets of 60-120lbs he had a little under 10,000 mg, for his weight toxic dose starts at 12,000 mg, so he should be safe, but if you start seeing worse symptoms or if he isn't better by tomorrow morning- take him to the vet in order to get it checked.

Thank you for submitting your question regarding Fiona. She is unlikely vomiting from the Trifexis if she hasn't in the past. That is a small dose change for her. There are numerous causes of vomiting such as dietary indiscretion, an infection, stress or something more serious such as eating a foreign object. If she still refuses to eat or cannot keep food or water down, then she will need to see a veterinarian today. Being such a small breed dog, it is easy for her to become dehydrated. If she seems to be feeling better, give her small frequent amounts of water and food throughout the day today. I hope this information helps!

Thank you for submitting your question regarding Junior. It is unlikely that he is experiencing a reaction from the vaccinations or the Trifexis given the amount of time in between. Reactions to both are possible, but in my experience will happen the same day. If his symptoms recur, I would recommend that he sees his veterinarian, but I am happy that he is feeling better now.

Diarrhea can be a side effect of any antiparasitic medication. As long as Butter is behaving normally otherwise, you can manage it at home. Withhold food for 12-24 hours. Allow small amounts of water or unflavored PediaLyte. Resume feeding a bland diet in small, frequent amount until symptoms resolve. Begin with 1 tablespoon of food every hour and gradually increase the amount. Feed bland until the stool is normal then transition slowly to the regular diet. Symptoms to monitor for and that should be addressed by your veterinarian include lethargy, vomiting, persistent diarrhea, loss of appetite or abdominal pain.