My 10-month puppy is lethargic, in pain, and vet meds aren't working.

From the sign you are describing it is quite difficult to determine the underlying problem. General signs of lethargy could be commonly due to high temperature which may be related to an infection. In puppies gastrointestinal and urinary tract infections are by far the most common type of infections. If the signs do not resolve in the next 24hours or if Luna is showing any inappetence, more evident lethargy or any other signs (vomiting and diarrhoea for example) I would strongly advice a veterinary check up.

Unfortunately, bloodwork will only tell us part of what is going on internally. Sometimes figuring out what is wrong can require additional testing such as urine samples, x-rays or ultrasounds. You didn't mention Luna's age, but have her listed as unspayed. Depending on when her last heat cycle was, you may want to discus with your veterinarian if she could have been bred or is having a uterine infection. Not eating or drinking is a serious medical problem, so I would strongly recommend contacting your veterinarian for their recommendation on the next diagnostic or treatment steps you can take with Luna to figure out what is going on and how to make her feel better. Good luck! I hope that was helpful. Thanks for using Petco Pet Education Center, formerly Petcoach.

Poor Luna! She may benefit from intravenous fluids. Have you veterinarian check some bloodwork to see if her liver or kidneys were affected. You may also ask your veterinarian if pain medication would be beneficial. Without being able to examine Luna myself, it's difficult to know how best to advise you. I hope she recovers quickly and please feel free to post any additional questions.

It definitely sounds like Lyra is sick, but her symptoms aren’t consistent with any specific disease process. I would recommend taking her back to the vet. Rechecking lab values will be helpful to see if there are any changes, and IV fluids would be helpful to fight inflammation and dehydration. She may need additional diagnostics like x-rays or an ultrasound to see what could be going on internally.

Poor Luna! It sounds like she needs to be examined by a vet to determine the cause of her lameness. She could have a strain/sprain, dislocation, or a fracture and your vet can take an x-ray to help diagnose and then determine the best way to treat. She might need an anti-inflammatory, splint, or possibly surgery to treat the problem. Hope she feels better soon!

Thank you for submitting your question regarding Luna. If there is nothing stuck in her throat, then I worry that she is coughing due to a respiratory tract infection. Has her veterinarian discussed the possibility of an upper respiratory tract infection or the more serious case of pneumonia? She may need antibiotics. I hope this information helps!

This sounds like abdominal pain, or back pain. Since she’s not spayed you need to be concerned about a uterine infection which could cause lethargy and abdominal discomfort. If she has a bulging disk in her back that can cause pain also. I would take her temperature to check for a fever, and if she has a fever or these symptoms continue then please bring her in for an exam and treatment. They will feel to find where she’s painful and may do an X-ray or blood tests to diagnose the problem. She’s a very small dog so please don’t wait too long since she doesn’t have the body reserves of a bigger dog. Thanks for using Petco Pet Education Center, formerly Petcoach to help you care for Luna.